70942-04-0

Basic information

• Product Name: 1-bromo-3-[4'-bromo(1,1'-biphenyl)-4-yl]-1,2,3,4-tetrahydronaphthalene
• Synonyms: 1-bromo-3-[4'-bromo(1,1'-biphenyl)-4-yl]-1,2,3,4-tetrahydronaphthalene
• CAS NO: 70942-04-0
• Molecular Formula: C₂₂H₁₈Br₂
• Molecular Weight: 442.18632
• EINECS: 275-032-3
• Mol File: 70942-04-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-bromo-3-[4'-bromo(1,1'-biphenyl)-4-yl]-1,2,3,4-tetrahydronaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-3-[4'-bromo(1,1'-biphenyl)-4-yl]-1,2,3,4-tetrahydronaphthalene(70942-04-0)
• EPA Substance Registry System: 1-bromo-3-[4'-bromo(1,1'-biphenyl)-4-yl]-1,2,3,4-tetrahydronaphthalene(70942-04-0)

Safety Data

• Hazardous Substances Data: 70942-04-0(Hazardous Substances Data)

Usage

General Description

1-bromo-3-[4'-bromo(1,1'-biphenyl)-4-yl]-1,2,3,4-tetrahydronaphthalene is a complex organic compound with a chemical formula of C22H19Br2. It is a derivative of naphthalene, containing two bromine atoms and a biphenyl group. This chemical is commonly used in organic synthesis and pharmaceutical research as a building block for more complex molecules. It has potential applications in the development of pharmaceutical drugs, agrochemicals, and materials science. Due to its intricate structure and functional groups, it is important for researchers to consider its reactivity, toxicity, and environmental impact when working with this compound in a laboratory setting.

Upstream product

• 56181-82-9 (+/-)-cis/trans-3-(4''-Bromobiphenyl-4'-yl)-1,2,3,4-tetrahydronaphthalen-1-ol 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 60312-95-0 1-[4'-bromo(1,1'-biphenyl)-4-yl]-2-phenylethan-1-one 
• 60313-01-1 3-(4''-Bromobiphenyl-4'-yl)-1,2,3,4-tetrahydronaphthalen-1-one 
• 103-80-0 phenylacetyl chloride 
• 124325-90-2 3-(4'-Bromo-biphenyl-4-yl)-4-phenyl-butyric acid ethyl ester 
• 124325-89-9 3-(4'-Bromo-biphenyl-4-yl)-4-phenyl-butyric acid 
• 124325-88-8 3-(4'-bromo-biphenyl-4-yl)-3-hydroxy-4-phenyl-butyric acid ethyl ester 

Downstream Products

• 56073-10-0 (3-[(1R,3S)-3-[4-(4-bromophenyl)phenyl]-1,2,3,4-tetrahydronaphthalen-1-yl]-4-hydroxychromen-2-one) 
• 56073-10-0 (3-[(1R,3R)-3-[4-(4-bromophenyl)phenyl]-1,2,3,4-tetrahydronaphthalen-1-yl]-4-hydroxychromen-2-one) 

Relevant articles and documents

Synthesis and antitumor activity of 4-hydroxycoumarin derivatives

A series of 4-hydroxycoumarin derivatives was prepared and evaluated for antitumor activity against five human tumor cell lines. A series of 4-hydroxycoumarin derivatives was prepared and evaluated for antitumor activity. The key fragments were 2a-c, 5c, 12b, 13b, 17, and 18 which were prepared via dianion ring cyclization, Friedel-Crafts acylation, and Reformatsky reaction. Compound 20b showed the most potent antitumor activity among the total 12 derivatives and compounds 19a and 19b exhibited efficacy comparable to etoposide in vitro antitumor activity.