70958-09-7Relevant articles and documents
Synthesis of 5-Arylpyrrole-2-carboxylic Acids as Key Intermediates for NBD Series HIV-1 Entry Inhibitors
Belov, Dmitry S.,Ivanov, Vladimir N.,Curreli, Francesca,Kurkin, Alexander V.,Altieri, Andrea,Debnath, Asim K.
, p. 3692 - 3699 (2017/08/15)
5-Arylpyrrole-2-carboxylic acids are important key intermediates in the synthesis of HIV-1 entry inhibitors (such as NBD-11021 and NBD-14010). Here we present a general method for the synthesis of some 5-arylpyrrole-2-carboxylic acids in three steps starting from pyrrole. By this method, the compounds could be prepared on gram scale and without chromatographic purification.
PYRROLES FROM KETOXIMES AND ACETYLENE. 38. NEW REPRESENTATIVES OF TRIFLUOROACETYLPYRROLES. SYNTHESIS AND TRANSFORMATIONS
Korostova, S. E.,Mikhaleva, A. I.,Sobenina, L. N.,Shevchenko, S. G.,Sigalov, M. V.,et al.
, p. 39 - 43 (2007/10/02)
A series of previously unknown trifluoroacetyl derivatives of pyrroles were obtained with high yields by the reaction of pyrroles, including N-vinyl-substituted pyrroles, with trifluoroacetic anhydride in the presence of pyridine at room temperature.The s
