709643-15-2Relevant articles and documents
A hemilabile diphosphine pyridine pincer ligand: σ- and π-binding in molybdenum coordination complexes
Agapie, Theodor,Buss, Joshua A.,Horak, Kyle T.,Wan, Ruomeng
, (2020)
A series of molybdenum compounds supported by a hemilabile pyridine diphosphine pincer ligand have been synthesized. The ligand demonstrates variable binding modes, adapting to the electronic and geometric requirements of the metal center. In Mo0 and MoII polycarbonyl complexes, coordination through the σ-donating pyridine nitrogen lone pair is observed. Upon oxidative group transfer with anionic azide, a MoIV nitride compound is formed, accompanied by a change in the ancillary ligand binding mode to the pyridine π-system. The σ-coordination was restored by subsequent functionalization of the nitride moiety with either silyl electrophiles or protons. Protonation results in redox disproportionation with concomitant nitride functionalization. Characterization by single crystal X-ray diffraction, nuclear magnetic resonance, and infrared spectroscopy is discussed.
Pd-Catalyzed Decarboxylation and Dual C(sp3)-H Functionalization Protocols for the Synthesis of 2,4-Diarylpyridines
Gujjarappa, Raghuram,Vodnala, Nagaraju,Kumar, Mohan,Malakar, Chandi C.
, p. 5005 - 5020 (2019/04/25)
The Pd-catalyzed decarboxylation and dual C(sp3)-H bond functionalization approaches have been described for the preparation of symmetrical and unsymmetrical 2,4-diarylpyridines. The developed transformations were realized using nonactivated aromatic ketones and amino acids as C-N sources. The efficacy of the catalyst and reagent combination drives the transformation toward the formation of desired products with high yields and selectivity. The described reaction conditions have seduced the self-reaction of phenylalanine via [2 + 2 + 2] cycloaddition and minimized the formation of 3,5-phenylpyridine as a side product, whereas using glycine as a C-N source, the corresponding 2,6-diarylpyridines were formed as minor products.
