70971-70-9

Basic information

• Product Name: 1H-Pyrrole, 1-(4-methylbenzoyl)-
• CAS NO: 70971-70-9
• Molecular Formula: C12H11NO
• Molecular Weight: 185.225
• Mol File: 70971-70-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole, 1-(4-methylbenzoyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole, 1-(4-methylbenzoyl)-(70971-70-9)
• EPA Substance Registry System: 1H-Pyrrole, 1-(4-methylbenzoyl)-(70971-70-9)

Safety Data

• Hazardous Substances Data: 70971-70-9(Hazardous Substances Data)

Upstream product

• 54582-33-1 1,1'-carbonyldiimidazole 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 1370360-25-0 4-methyl-N-(2,4,4-trimethoxybutyl)benzamide 
• 109-97-7 pyrrole 
• 201230-82-2 carbon monoxide 
• 624-31-7 4-tolyl iodide 
• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 619-55-6 para-methylbenzamide 
• 874-60-2 4-methyl-benzoyl chloride 

Downstream Products

• 69856-74-2 2-phenyl-2-(pyridin-4-yl)-1-(p-tolyl)ethan-1-one 
• 99-75-2 4-methyl-benzoic acid methyl ester 
• 23886-71-7 4-methoxy-4'-methylbenzophenone 
• 134-84-9 4-Methylbenzophenone 
• 109-97-7 pyrrole 
• 99-94-5 p-Toluic acid 

Relevant articles and documents

Suzuki-Miyaura Cross-Coupling of N-Acylpyrroles and Pyrazoles: Planar, Electronically Activated Amides in Catalytic N-C Cleavage

The formation of C-C bonds from amides by catalytic activation of the amide bond has been thus far possible by steric distortion. Herein, we report the first example of a general Pd-catalyzed Suzuki-Miyaura cross-coupling of planar amides enabled by the combination of (i) electronic-activation of the amide nitrogen in N-acylpyrroles and pyrazoles and (ii) the use of a versatile Pd-NHC catalysis platform. The origin and selectivity of forming acylmetals, including the role of twist, are discussed.

A practical preparation of highly versatile N-acylpyrroles from 2,4,4-trimethoxybutan-1-amine

A novel method for the preparation of N-acylpyrrole is described. The method involves condensation of carboxylic acids with 2,4,4-trimethoxybutan-1- amine, followed by acid-mediated cyclization to form the pyrrole ring. The preparative procedure is highly

Unique chemoselective Clauson-Kass reaction of substituted aniline catalyzed by MgI2 etherate

Clauson-Kass reaction of various substituted aniline, primary aryl amide, and sufonyl amide with 2,5-dimethoxytetrahydrofuran was realized in the presence of 10 mol % of MgI2 etherate in a mild, efficient, and highly chemoselective manner. Iodide counterion and solvents (i.e., MeCN) played the critical roles for the unique reactivity of this catalytic system.