70974-10-6

Basic information

• Product Name: 5,5-dimethyl-3-phenyl-imidazolidine-2,4-dione
• Synonyms: 5,5-dimethyl-3-phenyl-imidazolidine-2,4-dione
• CAS NO: 70974-10-6
• Molecular Formula: C₁₁H₁₂N₂O₂
• Molecular Weight: 0
• Mol File: 70974-10-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Density: 1.191g/cm³
• Refractive Index: 1.552
• CAS DataBase Reference: 5,5-dimethyl-3-phenyl-imidazolidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5,5-dimethyl-3-phenyl-imidazolidine-2,4-dione(70974-10-6)
• EPA Substance Registry System: 5,5-dimethyl-3-phenyl-imidazolidine-2,4-dione(70974-10-6)

Safety Data

• Hazardous Substances Data: 70974-10-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H12N2O2/c1-11(2)9(14)13(10(15)12-11)8-6-4-3-5-7-8/h3-7H,1-2H3,(H,12,15)

Upstream product

• 103-71-9 phenyl isocyanate 
• 19355-69-2 2-amino-2-cyanopropane 
• 77-71-4 5,5-dimethyl-imidazolidine-2,4-dione 
• 603-33-8 triphenylbismuthane 
• 98-80-6 phenylboronic acid 
• 62-57-7 2-Aminoisobutyric acid 
• 591-50-4 iodobenzene 
• 66003-76-7 Diphenyliodonium triflate 
• 144930-50-7 mesityl(phenyl)iodonium triflouromethanesulfonate 
• 115298-63-0 phenyl(4-methoxyphenyl)iodonium triflate 
• 1483-73-4 diphenyliodonium bromide 
• 58109-40-3 diphenyliodonium hexafluorophosphate 

Downstream Products

• 70974-09-3 5,5-dimethyl-3-(4-nitrophenyl)imidazolidine-2,4-dione 
• 1394916-83-6 1-([1,1'-biphenyl]-4-yl)-5,5-dimethyl-3-phenylimidazolidine-2,4-dione 
• 87976-13-4 5,5-dimethyl-1,3-diphenyl imidazolidine-2,4-dione 

Relevant articles and documents

N1- and N3-Arylations of Hydantoins Employing Diaryliodonium Salts via Copper(I) Catalysis at Room Temperature

Copper(I)-catalyzed N-arylation (both N1- and N3-) of hydantoins with diaryliodonium salts as aryl partners at room temperature is reported. The transformation allows diverse scopes on both hydantoins and diaryliodonium salts deliver

Copper-Mediated N-Arylations of Hydantoins

A set of two broadly applicable procedures for the N-arylation of hydantoins is reported. The first one relies on the use of stoichiometric copper(I) oxide under ligand- A nd base-free conditions and enables a clean regioselective arylation at the N3 nitrogen atom, while the second one is based on the use of catalytic copper(I) iodide and trans-N,N′-dimethylcyclohexane-1,2-diamine and promotes arylation at the N1 nitrogen atom. Importantly, the combination of these two procedures affords a straightforward entry to diarylated hydantoins.

Comparison of copper(II) acetate promoted N-arylation of 5,5-dimethyl hydantoin and other imides with triarylbismuthanes and aryl boronic acids

This work demonstrates that the copper acetate promoted N-arylation of imides with boronic acids can be employed as a major method for the synthesis of N3-aryl hydantoins. Georg Thieme Verlag Stuttgart.