70978-39-1 Usage
Description
5'-FLUORO-2'-HYDROXY-3'-NITRO-, also known as 5'-Fluoro-2'-hydroxy-3'-nitroacetophenone, is an organic compound that serves as an important intermediate in the synthesis of various pharmaceuticals and chemical compounds. Its unique structure, featuring a fluorine atom at the 5' position, a hydroxyl group at the 2' position, and a nitro group at the 3' position, endows it with specific chemical properties that make it a valuable building block in organic synthesis.
Uses
Used in Pharmaceutical Synthesis:
5'-FLUORO-2'-HYDROXY-3'-NITROis used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique functional groups allow for further chemical reactions and modifications, leading to the development of new drugs with improved therapeutic properties.
Used in Organic Synthesis:
In the field of organic synthesis, 5'-FLUORO-2'-HYDROXY-3'-NITROis used as a versatile building block for the preparation of a wide range of organic compounds. Its reactivity and functional groups make it suitable for various synthetic routes, enabling the creation of complex molecules with diverse applications.
Used in Catalyst Preparation:
5'-FLUORO-2'-HYDROXY-3'-NITROcan be used in the preparation of catalysts for various chemical reactions. Its ability to participate in catalytic cycles and its stability under certain reaction conditions make it a promising candidate for the development of new catalysts.
Used in the Preparation of 1-(3-amino-5-fluoro-2-hydroxyphenyl)ethanone:
5'-FLUORO-2'-HYDROXY-3'-NITROis used as a starting material to prepare 1-(3-amino-5-fluoro-2-hydroxyphenyl)ethanone via catalytic hydrogenation. This transformation allows for the synthesis of a new compound with potential applications in various fields, such as pharmaceuticals or materials science.
Preparation
Preparation by nitration of 5-fluoro-2-hydroxy-acetophenone with nitric acid (d = 1.42) in concentrated sulfuric acid between ?15° and ?5° (46%).
Check Digit Verification of cas no
The CAS Registry Mumber 70978-39-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,9,7 and 8 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 70978-39:
(7*7)+(6*0)+(5*9)+(4*7)+(3*8)+(2*3)+(1*9)=161
161 % 10 = 1
So 70978-39-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H6FNO4/c1-4(11)6-2-5(9)3-7(8(6)12)10(13)14/h2-3,12H,1H3
70978-39-1Relevant articles and documents
ANTI-INFECTIVE AGENTS
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Page/Page column 171-172, (2018/04/12)
The present invention relates to a novel class of chromene-2-carboxamide compounds inhibitors of general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8 and X are as defined herein, to their use in medicine, and their use as anti-infective agents in particular, to compositions containing them, to processes for their preparation and to intermediates used in such processes.
MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS
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Page/Page column 73; 74, (2015/05/26)
The present invention relates to compounds compound according to Formula (III); and pharmaceutically acceptable salts, hydrates and solvates thereof. These compounds have D2receptor antagonist/(partial) agonist effects and H3antagonistic effects, pharmaceutical compositions thereof, and methods of using them for application in the prophylaxis or treatment of CNS disorders.
SUBSTITUTED PYRAZOLO[1,5-A] PYRIDINE AS TROPOMYOSIN RECEPTOR KINASE (TRK) INHIBITORS
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Page/Page column 71-72, (2013/07/05)
The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors., method of making and pharmaceutical compositions comprising such compounds.
