70989-89-8

Basic information

• Product Name: L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-, pentafluorophenyl ester
• CAS NO: 70989-89-8
• Molecular Formula: C22H22F5NO5
• Molecular Weight: 475.412
• Mol File: 70989-89-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-, pentafluorophenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-, pentafluorophenyl ester(70989-89-8)
• EPA Substance Registry System: L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-, pentafluorophenyl ester(70989-89-8)

Safety Data

• Hazardous Substances Data: 70989-89-8(Hazardous Substances Data)

Upstream product

• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 15260-10-3 N-Boc-O-benzyl-L-threonine 
• 96157-57-2 bis(pentafluorophenyl)sulfite 

Downstream Products

• 61884-24-0 [(1S,2R)-2-Benzyloxy-1-((S)-2-carbamoyl-pyrrolidine-1-carbonyl)-propyl]-carbamic acid tert-butyl ester 
• 78058-23-8 Z-pGlu-Thr(Bzl)-Pro-NH₂ 
• 78058-22-7 (S)-1-((2S,3R)-2-Amino-3-benzyloxy-butyryl)-pyrrolidine-2-carboxylic acid amide; hydrochloride 
• 140702-20-1 Boc-Cys(Bzl)-Met-Thr(Bzl)-Thr(Bzl)-Ala-Gln-Gly-OH 
• 140684-56-6 {(S)-2-[(S)-2-((2S,3R)-2-{(2S,3R)-2-[(S)-2-((R)-2-Amino-3-benzylsulfanyl-propionylamino)-4-methylsulfanyl-butyrylamino]-3-benzyloxy-butyrylamino}-3-benzyloxy-butyrylamino)-propionylamino]-4-carbamoyl-butyrylamino}-acetic acid 
• 140702-18-7 Boc-Met-Thr(Bzl)-Thr(Bzl)-Ala-Gln-Gly-OH 
• 140702-19-8 [(S)-2-((S)-2-{(2S,3R)-2-[(2S,3R)-2-((S)-2-Amino-4-methylsulfanyl-butyrylamino)-3-benzyloxy-butyrylamino]-3-benzyloxy-butyrylamino}-propionylamino)-4-carbamoyl-butyrylamino]-acetic acid 
• 140702-17-6 Boc-Thr(Bzl)-Thr(Bzl)-Ala-Gln-Gly-OH 
• 140696-54-4 Thr(Bzl)-Ala-Gln-Gly-OH 
• 140684-57-7 Boc-Thr(Bzl)-Cys(Bzl)-Met-Thr(Bzl)-Thr(Bzl)-Ala-Gln-Gly-OH 
• 140685-17-2 Boc-Thr(Bzl)-Ser(Bzl)-Met-Tyr(Bzl)-Pro-Ser-Cys(Bzl)-NH₂ 
• 764693-24-5 N-(triisopropylsilyloxycarbonyl)-O-(benzyl)-L-threonine pentafluorophenyl ester 
• 54613-92-2 Boc-Thr(Bzl)-Ser(Bzl)-OH 
• 140685-14-9 Boc-Thr(Bzl)-Ser(Bzl)-Met-Tyr(Bzl)-Pro-OH 

Relevant articles and documents

Chemical synthesis of 23 kDa glycoprotein by repetitive segment condensation: A synthesis of MUC2 basal motif carrying multiple O-GalNAc moieties

Peptide thioester corresponding to a MUC2 tandem repeat unit, which retains seven GalNAc moieties, was prepared by the Fmoc method followed by the low TfOH treatment to remove benzyl groups at the carbohydrate portions. The glycosylated peptide thioester was then consecutively joined by the activation of a thioester group by silver ions to obtain a MUC2 tandem repeat model composed of 141 amino acids with 42 GalNAc moieties.