71005-54-4

Basic information

• Product Name: (Z)-2-(2-hydroxybenzylidene)-6-methoxybenzofuran-3(2H)-one
• Synonyms: (Z)-2-(2-hydroxybenzylidene)-6-methoxybenzofuran-3(2H)-one
• CAS NO: 71005-54-4
• Molecular Weight: 268.269
• Mol File: 71005-54-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Z)-2-(2-hydroxybenzylidene)-6-methoxybenzofuran-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-(2-hydroxybenzylidene)-6-methoxybenzofuran-3(2H)-one(71005-54-4)
• EPA Substance Registry System: (Z)-2-(2-hydroxybenzylidene)-6-methoxybenzofuran-3(2H)-one(71005-54-4)

Safety Data

• Hazardous Substances Data: 71005-54-4(Hazardous Substances Data)

Upstream product

• 15832-09-4 6-methoxy-3-coumaranone 
• 90-02-8 salicylaldehyde 
• 6272-26-0 6-hydroxybenzofuran-3-one 

Relevant articles and documents

Synthesis of aurones and their inhibitory effects on nitric oxide and PGE2 productions in LPS-induced RAW 264.7 cells

Sulfuretin is one of major constituents of Rhus verniciflua that exerts anti-inflammatory activities. Some of aurones were synthesized as sulfuretin derivatives and evaluated for their abilities to inhibit NO and PGE2 production in LPS-induced RAW 264.7 cells in order to reveal the relationship. Of the aurones synthesized in the present study, 2h and 2i, which possess C-6 hydroxyl group in A-ring and methoxy substituents in B-ring, more potently inhibited NO and PGE2 production and were less cytotoxic than sulfuretin.