71023-10-4Relevant articles and documents
Two-Step Chemoenzymatic Detection of N-Acetylneuraminic Acid-α(2-3)-Galactose Glycans
Wen, Liuqing,Zheng, Yuan,Jiang, Kuan,Zhang, Mingzhen,Kondengaden, Shukkoor Muhammed,Li, Shanshan,Huang, Kenneth,Li, Jing,Song, Jing,Wang, Peng George
, p. 11473 - 11476 (2016/10/07)
Sialic acids are typically linked α(2-3) or α(2-6) to the galactose that located at the non-reducing terminal end of glycans, playing important but distinct roles in a variety of biological and pathological processes. However, details about their respective roles are still largely unknown due to the lack of an effective analytical technique. Herein, a two-step chemoenzymatic approach for the rapid and sensitive detection of N-acetylneuraminic acid-α(2-3)-galactose glycans is described.
