71031-48-6

Basic information

• Product Name: 4-HYDROXY-3-IODOBIPHENYL 95
• Synonyms: 4-HYDROXY-3-IODOBIPHENYL 95;3-iodo-(1,1'-biphenyl)-4-ol;3-Iodo-(1,1μ-biphenyl)-4-ol, 3-Iodo-4-phenylphenol;4-Hydroxy-3-iodobiphenyl 95%
• CAS NO: 71031-48-6
• Molecular Formula: C₁₂H₉IO
• Molecular Weight: 296.1
• Mol File: 71031-48-6.mol
• Article Data: 19

Chemical Properties

• Melting Point: 115-119 °C(lit.)
• Boiling Point: 326.4°C at 760 mmHg
• Flash Point: 151.2°C
• Appearance: /
• Density: 1.689g/cm³
• Vapor Pressure: 0.000114mmHg at 25°C
• Refractive Index: 1.672
• CAS DataBase Reference: 4-HYDROXY-3-IODOBIPHENYL 95(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXY-3-IODOBIPHENYL 95(71031-48-6)
• EPA Substance Registry System: 4-HYDROXY-3-IODOBIPHENYL 95(71031-48-6)

Safety Data

• Hazard Codes: Xi,N
• Statements: 38-41-51/53
• Safety Statements: 26-36/37/39-61
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 71031-48-6(Hazardous Substances Data)

Usage

General Description

4-HYDROXY-3-IODOBIPHENYL 95 is a chemical compound consisting of a biphenyl ring with a hydroxyl group and an iodine atom attached to it. It is used in organic synthesis and pharmaceutical research as a building block for the production of various other chemicals and drugs. 4-HYDROXY-3-IODOBIPHENYL 95 is also used as a precursor in the manufacture of dyes and pigments. Additionally, it has potential applications in the field of material science and as a reagent in chemical reactions. 4-HYDROXY-3-IODOBIPHENYL 95 is known for its versatility and has a wide range of uses in different industries.

InChI:InChI=1/C12H9IO/c13-11-8-10(6-7-12(11)14)9-4-2-1-3-5-9/h1-8,14H

Upstream product

• 92-69-3 4-Phenylphenol 
• 7790-99-0 Iodine monochloride 
• 64-19-7 acetic acid 
• 7664-41-7 ammonia 
• 7553-56-2 iodine 
• 91718-20-6 3-iodo-4-methoxy-1,1′-biphenyl 
• 956219-15-1 C₁₆H₁₇NO₂ 

Downstream Products

• 121045-39-4 5-methyl-2-phenylbenzofuran 
• 78210-31-8 2-phenyldibenzo[b,d]furan 
• 91718-20-6 3-iodo-4-methoxy-1,1′-biphenyl 
• 958236-38-9 C₂₉H₂₆O₅ 
• 1072840-35-7 1-(1-ethoxyethoxy)-2-iodo-4-phenyl-benzene 
• 1202754-29-7 3-(4-methoxybenzyl)-7-phenyl-4-tosyl-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one 

Relevant articles and documents

-

-

Palladium-Catalyzed Chemoselective Oxidative Addition of Allyloxy-Tethered Aryl Iodides: Synthesis of Medium-Sized Rings and Mechanistic Studies

This Letter describes a Pd-catalyzed Tsuji-Trost-type/Heck reaction with allyloxy-tethered aryl iodides and aziridines. The strategy provides efficient access to benzannulated medium-sized rings via intermolecular cyclization. The substrate aryl iodide ha

Pd-Catalyzed ipso, meta-Dimethylation of ortho-Substituted Iodoarenes via a Base-Controlled C-H Activation Cascade with Dimethyl Carbonate as the Methyl Source

A methyl group can have a profound impact on the pharmacological properties of organic molecules. Hence, developing methylation methods and methylating reagents is essential in medicinal chemistry. We report a palladium-catalyzed dimethylation reaction of ortho-substituted iodoarenes using dimethyl carbonate as a methyl source. In the presence of K2CO3 as a base, iodoarenes are dimethylated at the ipso- and meta-positions of the iodo group, which represents a novel strategy for meta-C-H methylation. With KOAc as the base, subsequent oxidative C(sp3)-H/C(sp3)-H coupling occurs; in this case, the overall transformation achieves triple C-H activation to form three new C-C bonds. These reactions allow expedient access to 2,6-dimethylated phenols, 2,3-dihydrobenzofurans, and indanes, which are ubiquitous structural motifs and essential synthetic intermediates of biologically and pharmacologically active compounds.