71050-29-8

Basic information

• Product Name: 4,4'-methylenebis(N,N,3-trimethyl-Benzenamine
• Synonyms: 4,4'-methylenebis(N,N,3-trimethyl-Benzenamine;4,4'-Bis(dimethylamino)-2,2'-dimethyldiphenylmethane;4,4'-Methylenebis(N,N-dimethyl-3-methylbenzenamine)
• CAS NO: 71050-29-8
• Molecular Formula: C₁₉H₂₆N₂
• Molecular Weight: 282.42
• Mol File: 71050-29-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 434.6±40.0 °C(Predicted)
• Appearance: /
• Density: 1.018±0.06 g/cm3(Predicted)
• PKA: 5.70±0.22(Predicted)
• CAS DataBase Reference: 4,4'-methylenebis(N,N,3-trimethyl-Benzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-methylenebis(N,N,3-trimethyl-Benzenamine(71050-29-8)
• EPA Substance Registry System: 4,4'-methylenebis(N,N,3-trimethyl-Benzenamine(71050-29-8)

Safety Data

• Hazardous Substances Data: 71050-29-8(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 121-72-2 N,N-dimethyl-m-toluidine 
• 141-52-6 sodium ethanolate 
• 67-68-5 dimethyl sulfoxide 

Downstream Products

• 860573-04-2 bis-[4-(cyano-methyl-amino)-2-methyl-phenyl]-methane 
• 43001-46-3 4,4'-Bis-dimethylamino-2,2'-dimethyl-benzhydrol 

Relevant articles and documents

Highly regioselective para-methylthiolation/bridging methylenation of arylamines promoted by NH4I

Aryl methyl thioethers and methylene-bridged arylamines were synthesized via highly regioselective para-methylthiolation/bridging methylenation of arylamines using DMSO as the methylthio or methylene source in the presence of NH4I under metal-free conditions. For the substrates with both electron-donating and electron-withdrawing substituents, the reaction proceeded smoothly and gave moderate to good yields.

PHOSPHORUS-NITROGEN COMPOUNDS. PART 48. THE REACTIONS OF N,N-DIMETHYLTOLUIDINES WITH PHOSPHORUS(V) CHLORIDES. FORMATION OF A NOVEL HETEROCYCLIC SYSTEM.

The reactions of phosphorus oxychloride, P(O)Cl3, with the three N,N-dimethyltoluidines have been studied.O-toluidine gave after suitable work-up only a "nitrogen-substituted" derivative, P(O)(NMeC6H4Me-2)(OEt)2, whilst the m-analogue gave both "nitrogen-substituted", P(O)(NMeC6H4Me-3)(OEt)2, and "carbon-substituted" products, P(O)(C6H3Me-2-NMe2-4)2(OEt), as well as two purely organic compounds, CH2(C6H3Me-2-NMe2-4)2 and CH(C6H3Me-2-NMe2-4)3.With N,N-dimethyl-p-toluidine in addition to two acyclic 'nitrogen-substituted' products, P(O)(NMeC6H4Me-4)(OEt)2 and P(O)(NMeC6H4Me-4)2(OEt), the chloro- and ethoxy-derivative of a novel eight-membered heterocyclic system, P(O)X (X = Cl or OEt), as well as two organic products, CH2(C6H3Me-5-NHMe-2)2 and CH2(C6H3Me-5-NMe2-2)-(C6H3Me-5-NHMe-2) were isolated.The reaction of thiophosphoryl chloride, P(S)Cl3, with N,N-dimethyl-p-toluidine also gave a similar heterocycle, P(S)Cl.The 1H NMR spectra are discussed and related to the X-ray crystal structures.