71056-57-0

Basic information

• Product Name: ETHYL 1-METHYL-5-NITROINDOLE-2-CARBOXYLATE
• Synonyms: ETHYL 1-METHYL-5-NITROINDOLE-2-CARBOXYLATE;ethyl 1-methyl-5-nitro-1H-indole-2-carboxylate
• CAS NO: 71056-57-0
• Molecular Formula: C₁₂H₁₂N₂O₄
• Molecular Weight: 248.23
• Mol File: 71056-57-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ETHYL 1-METHYL-5-NITROINDOLE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 1-METHYL-5-NITROINDOLE-2-CARBOXYLATE(71056-57-0)
• EPA Substance Registry System: ETHYL 1-METHYL-5-NITROINDOLE-2-CARBOXYLATE(71056-57-0)

Safety Data

• Hazardous Substances Data: 71056-57-0(Hazardous Substances Data)

Upstream product

• 16732-57-3 5-nitro-indole-2-carboxylic acid ethyl ester 
• 80-48-8 methyl p-toluene sulfonate 
• 74-88-4 methyl iodide 

Downstream Products

• 833427-09-1 6-(4-chlorophenyl)-3-[1-methyl-2-(pyrrolidin-1-ylmethyl)-1H-indol-5-yl]thieno[3,2-d]pyrimidin-4(3H)-one 
• 71056-58-1 5-amino-1-methyl-1H-indole-2-carboxylic acid ethyl ester 

Relevant articles and documents

1-(CYCLOALKYL-CARBONYL)PROLINE DERIVATIVE

A compound represented by formula (1) (in the formula: ring-D represents a three- to eight-membered hydrocarbon ring; Ra represents an optionally substituted amino C1-6 alkyl group or the like; Rb1 and Rb2 each independently represent a hydrogen atom, a halogen atom, or the like; Rc represents an optionally substituted C6-10 aryl group or the like; Rd represents a hydrogen atom or the like; and ring-Q represents a (hetero)aryl group or the like which may be substituted with a carboxyl group or the like) or a pharmaceutically acceptable salt thereof exhibits an excellent FXIa inhibitory activity, and is useful as a therapeutic agent against thrombosis or the like.

Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals

The present invention relates to aminoalkyl-substituted aromatic bicyclic compounds of formula I, which are valuable pharmaceutically active compounds that are suitable, for example, for the treatment of obesity, type II diabetes, arteriosclerosis, high blood pressure, paresthesia, depression, anxiety, anxiety neuroses, schizophrenia, disorders associated with the circadian rhythm, and drug abuse, as well as normalizing lipid metabolism.

INDOLOYLGUANIDINE DERIVATIVES

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