711-79-5Relevant articles and documents
Hauser,Rhee
, p. 178 (1978)
Manganese triacetate oxidation of methyl 1-hydroxy-2-naphthalene carboxylates
Munive, Laura,Gómez-Calvario, Víctor,Olivo, Horacio F.
, p. 2445 - 2447 (2017)
Manganese-triacetate mediated oxidation of 1-hydroxy-2-napthalene carboxylates in benzene under anhydrous conditions delivers the dimerized product. However, acetoxylation on the ortho- or para-position, or oxidation to quinones occurs on the 1-hydroxy-3-substituted 2-napthalene carboxylates depending on the nature of the substituents when the reaction is carried out in a mixture of acetic acid/acetonitrile.
Synthesis and supramolecular structure of 2-acetyl-1-naphthol
Su, Qiong,Zhang, Xin-Ying,Zhang, Yu-Jie,Zhao, Li,Wang, Li,Wang, Yan-Bin
, p. 5115 - 5116 (2013)
2-Acetyl-1-naphthol with the molecular formula C12H10O2, is stabilized by intramolecular O2-H2...O1 hydrogen bond forming a six-membered ring, nearly planar with the naphthone ring and the distances from C1 atom of acetyl group to mean plane of the three six-membered ring is 0.112(3) ?. Moreover, the structure is stabilized by intermolecular C-H...p and p-p stacking interactions.
Directed Hydroxylation of sp2 and sp3 C-H Bonds Using Stoichiometric Amounts of Cu and H2O2
Trammell, Rachel,D'Amore, Lorenzo,Cordova, Alexandra,Polunin, Pavel,Xie, Nan,Siegler, Maxime A.,Belanzoni, Paola,Swart, Marcel,Garcia-Bosch, Isaac
, p. 7584 - 7592 (2019/06/11)
The use of copper for C-H bond functionalization, compared to other metals, is relatively unexplored. Herein, we report a synthetic protocol for the regioselective hydroxylation of sp2 and sp3 C-H bonds using a directing group, stoichiometric amounts of Cu and H2O2. A wide array of aromatic ketones and aldehydes are oxidized in the carbonyl γ-position with remarkable yields. We also expanded this methodology to hydroxylate the β-position of alkylic ketones. Spectroscopic characterization, kinetics, and density functional theory calculations point toward the involvement of a mononuclear LCuII(OOH) species, which oxidizes the aromatic sp2 C-H bonds via a concerted heterolytic O-O bond cleavage with concomitant electrophilic attack on the arene system.
ATF3 INDUCTION COMPOUNDS
-
, (2018/10/19)
Provided are compounds for treating and/or preventing obesity and obesity-related disorders. Particularly, provided are chromanone derivatives used as ATF3 inducer and for treating and/or preventing obesity and obesity-related disorders such as heart disease, hypertension, hyperlipidemia and diabetes.