71116-82-0

Basic information

• Product Name: Tiaprost
• Synonyms: Tiaprost;7-[3,5-Dihydroxy-2-[3-hydroxy-4-(3-thienyloxy)-1-butenyl]cyclopentyl]-5-heptenoic acid;Tiaprost(Iliren);(E)-7-[3,5-dihydroxy-2-[(E)-3-hydroxy-4-thiophen-3-yloxybut-1-enyl]cyclopentyl]hept-5-enoic acid;FYBFDIIAPRHIQS-JRSBLEPXSA-N
• CAS NO: 71116-82-0
• Molecular Formula: C20H28O6S
• Molecular Weight: 396.5
• Mol File: 71116-82-0.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 613.4 °C at 760 mmHg
• Flash Point: 324.8 °C
• Appearance: /
• Density: 1.325 g/cm³
• Vapor Pressure: 6.69E-16mmHg at 25°C
• Refractive Index: 1.633
• PKA: 4.79±0.10(Predicted)
• CAS DataBase Reference: Tiaprost(CAS DataBase Reference)
• NIST Chemistry Reference: Tiaprost(71116-82-0)
• EPA Substance Registry System: Tiaprost(71116-82-0)

Safety Data

• RIDADR: 3249
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 71116-82-0(Hazardous Substances Data)

Usage

Description

Tiaprost is a synthetic analog of prostaglandin F2α (PGF2α), a naturally occurring hormone that plays a significant role in various physiological processes. It is primarily known for its effects on the reproductive system, particularly in the context of luteolysis, which is the process of the regression of the corpus luteum, a temporary endocrine structure in the ovary that produces progesterone.

Uses

Used in Veterinary Medicine:
Tiaprost is used as an estrus-synchronizing agent in veterinary medicine. This application is crucial for the management of breeding programs in livestock, as it helps to synchronize the estrous cycles of multiple animals, allowing for more efficient and controlled breeding practices.
Used in Treatment of Endometritis:
Tiaprost is also utilized in the treatment of endometritis, an inflammation of the endometrium, which is the inner lining of the uterus. This condition can lead to infertility and other complications in animals, and Tiaprost's ability to mimic the effects of PGF2α helps to alleviate the symptoms and promote healing.
Used in Induction of Parturition:
In addition to its other applications, Tiaprost is used to induce parturition, or the process of giving birth. By mimicking the effects of PGF2α, Tiaprost can help to initiate the contractions necessary for labor, which can be particularly useful in cases where natural labor is delayed or not progressing as expected.

InChI:InChI=1/C20H28O6S/c21-14(12-26-15-9-10-27-13-15)7-8-17-16(18(22)11-19(17)23)5-3-1-2-4-6-20(24)25/h1,3,7-10,13-14,16-19,21-23H,2,4-6,11-12H2,(H,24,25)/b3-1-,8-7+/t14?,16-,17-,18+,19-/m1/s1