71119-01-2

Basic information

• Product Name: 2-bromo-4-(methoxymethyl)phenol
• Synonyms: 2-bromo-4-(methoxymethyl)phenol
• CAS NO: 71119-01-2
• Molecular Weight: 217.062
• Mol File: 71119-01-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-bromo-4-(methoxymethyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-4-(methoxymethyl)phenol(71119-01-2)
• EPA Substance Registry System: 2-bromo-4-(methoxymethyl)phenol(71119-01-2)

Safety Data

• Hazardous Substances Data: 71119-01-2(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 6627-55-0 2-bromo-p-cresol 
• 29922-56-3 2-bromo-4-(hydroxymethyl)phenol 
• 2973-78-6 3-bromo-4-hydroxybenzylaldehyde 

Downstream Products

• 5533-03-9 2-methoxy-4-methoxymethylphenol 

Relevant articles and documents

Synthesis of Benzothieno[60]fullerenes through Fullerenyl Cation Intermediates

Benzothieno[60]fullerenes were synthesized using fullerenyl cations as key intermediates. The reaction proceeded through a nucleophilic attack of the sulfur atom as a weak nucleophile to the fullerenyl cation electrophile. A monoarylated fullerene, (2-methylthiophenyl)hydro[60]fullerene, C60ArH (Ar = C6H4-SMe-2 and so on; four derivatives) was subjected to deprotonation with KOtBu to form a fullerenyl anion ArC60-, followed by oxidation using I2 to generate a fullerenyl cation ArC60+, leading to intramolecular demethylative cyclization via fullerene cation-S interaction to the product. Electrochemical and computational studies revealed slightly narrower band gap of this compound than usual fullerene derivatives because of the relatively high-lying HOMO of the fused thieno moiety.

A highly efficient approach to vanillin starting from 4-cresol

A highly efficient approach to the famous flavor and fragrance compound vanillin has been developed starting from 4-cresol with the attention focused on improving the sustainability of all the reactions. The approach involves a three-step sequence of the quasi-quantitative selective clean oxybromination of 4-cresol, the high-yield selective aerobic oxidation of 2-bromo-4-cresol, and the quantitative methoxylation of 3-bromo-4-hydroxybenzaldehyde with the recovery of pure methanol. Herein, the pivotal oxidation and methoxylation reactions are logically investigated and developed into two concise methodologies. As a green alternative, the approach holds significant value for the sustainable manufacturing of vanillin. the Partner Organisations 2014.