71144-39-3 Usage
Description
5-fluorodopamine is a synthetic chemical and a fluorinated analog of dopamine, a neurotransmitter crucial for movement and mood regulation. It is utilized in scientific research to investigate the impacts of Parkinson's disease and other neurological disorders.
Used in Scientific Research:
5-fluorodopamine is used as a research tool for studying the effects of Parkinson's disease and other neurological disorders due to its ability to selectively destroy dopamine-producing neurons in laboratory animals, enabling the examination of resulting motor and behavioral deficits.
Used in Pharmaceutical Development:
5-fluorodopamine is used as a potential treatment candidate for certain neurological conditions, given its interaction with the dopaminergic system and its effects on motor and behavioral functions.
Used in Neurodegenerative Disease Studies:
In the field of neurodegenerative disease research, 5-fluorodopamine is used as a means to induce Parkinson's-like symptoms in animal models, providing valuable insights into the disease's progression and potential therapeutic interventions.
Check Digit Verification of cas no
The CAS Registry Mumber 71144-39-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,1,4 and 4 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 71144-39:
(7*7)+(6*1)+(5*1)+(4*4)+(3*4)+(2*3)+(1*9)=103
103 % 10 = 3
So 71144-39-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H10FNO2.BrH/c9-6-4-8(12)7(11)3-5(6)1-2-10;/h3-4,11-12H,1-2,10H2;1H
71144-39-3Relevant articles and documents
Fast enzymatic synthesis of n.c.a. 6-[18F]fluorodopamine (FDA) from n.c.a. 6-[18F]FDOPA and the fate of 6-FDOPA and 6-FDA in neuroblastoma and Caki-1 cells after their uptake
Ku?i, Zyrafete,Ehrlichmann, Walter,Sauer, J?rg,Handgretinger, Rupert,Bruchelt, Gernot,Reischl, Gerald
, p. 438 - 447 (2019/07/18)
The catecholamine analogue [123I]mIBG has been used for scintigraphic imaging of neuroblastoma since 1984. It is taken up by the noradrenaline transporter (NAT), which is present in most neuroblastoma cells. An alternative imaging method could
