7115-46-0

Basic information

• Product Name: 1-DEOXY-1-(METHYLAMINO)-D-GALACTITOL
• Synonyms: 1-DEOXY-1-(METHYLAMINO)-D-GALACTITOL;1-DEOXY-1-(METHYLAMINO)-D-GALACTITOL 9&
• CAS NO: 7115-46-0
• Molecular Formula: C₇H₁₇NO₅
• Molecular Weight: 195.21
• Mol File: 7115-46-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 133-136 °C(lit.)
• Boiling Point: 490.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.375±0.06 g/cm3(Predicted)
• Refractive Index: 1.555
• PKA: 13.47±0.20(Predicted)
• CAS DataBase Reference: 1-DEOXY-1-(METHYLAMINO)-D-GALACTITOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-DEOXY-1-(METHYLAMINO)-D-GALACTITOL(7115-46-0)
• EPA Substance Registry System: 1-DEOXY-1-(METHYLAMINO)-D-GALACTITOL(7115-46-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 7115-46-0(Hazardous Substances Data)

Usage

Uses

D-(-)-N-Methylgalactamine is used as a starting material for the preparation of sulfoximine-nicotine derivatives that are kinase inhibitors useful in the treatment of proliferative diseases as well as novel tricyclic benzodiazepine carboxamides that are tocolytic oxytocin receptor antagonists.

InChI:InChI=1/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7-/m0/s1

Upstream product

• 59-23-4 D-Galactose 
• 74-89-5 methylamine 
• 2280-44-6 D-Glucose 

Downstream Products

• 7057-03-6 1--phenylcarbamoyl)-amino>-1-desoxy-D-dulcit 
• 7115-58-4 1--phenyl-thiocarbamoyl)-amino>-1-desoxy-D-dulcit 
• 7115-63-1 1--1-desoxy-D-dulcit 
• 7115-51-7 1--1-desoxy-D-dulcit 
• 74-93-1 methylthiol 
• 113224-27-4 C₁₀H₁₇N₅O₅ 
• 113224-26-3 C₉H₁₇N₅O₇ 
• 34081-28-2 D_r-1t_F,2t_F,3r_F,4-tetraacetoxy-1cat_F-((5S)-3-methyl-2t-phenyl-oxazolidin-5r-yl)-butane 
• 439080-76-9 1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-{4-[methyl-(2,3,4,5,6-pentahydroxyhexyl)amino]butoxy}phenyl)azetidin-2-one 
• 439080-78-1 1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-{5-[methyl-(2,3,4,5,6-pentahydroxyhexyl)amino]pentyloxy}phenyl)azetidin-2-one 
• 439080-80-5 1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-{6-[methyl-(2,3,4,5,6-pentahydroxyhexyl)amino]hexyloxy}phenyl)azetidin-2-one 
• 439080-82-7 1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-{8-[methyl-(2,3,4,5,6-pentahydroxyhexyl)amino]octyloxy}phenyl)azetidin-2-one 
• 439080-84-9 1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-{10-[methyl-(2,3,4,5,6-pentahydroxyhexyl)amino]decyloxy}phenyl)azetidin-2-one 
• 265121-04-8 Fosaprepitant dimeglumine 

Relevant articles and documents

Process for the preparation of N-alkypolyhydroxyalkylamines from monoalkylamine and reducing sugar

Aqueous, alcoholic or aqueous-alcoholic solutions of a monoalkylamine and a reducing sugar are simultaneously injected into a mixing unit and the two solutions are mixed under turbulence in the mixing unit for 6 seconds to 5 minutes at a temperature of 25 to 60° C. and a pressure of 50 to 90 bar. The mixture is then added to a hydrogenation reactor and hydrogenated with hydrogen in the presence of a hydrogenation catalyst. An alkylpolyhydroxyalkylamine is obtained in high yield and with high purity.