71154-12-6Relevant articles and documents
Addition of α-Halonitriles to Carbonyl Compounds Catalyzed by Zinc-Trimethylchlorosilane: A General Synthesis of β-Trimethylsiloxy Nitriles
Palomo, Claudio,Aizpurua, Jesus M.,Lopez, M. Concepcion,Aurrekoetxea, Natalia
, p. 2205 - 2208 (2007/10/02)
Reaction between bromoacetonitrile and carbonyl compounds in the presence of zinc and trimethylchlorosilane produced β-trimethylsilyloxynitriles in excellent yields.The reaction also works well with chloroacetonitrile as source of cyanomethyl carbanion.