71235-00-2 Usage
Description
4,4,4-TriMethoxybutanoic Acid Methyl Ester is an organic compound that serves as an important intermediate in the synthesis of various pharmaceuticals and chemicals. It is characterized by its ester functional group and three methoxy substituents on the butanoic acid backbone, which contribute to its reactivity and versatility in chemical reactions.
Uses
Used in Pharmaceutical Industry:
4,4,4-TriMethoxybutanoic Acid Methyl Ester is used as a key synthetic intermediate for the production of Methyl Prednisolone (M325934), a corticosteroid medication. It plays a crucial role in the synthesis process, enabling the formation of the desired pharmaceutical compound with improved efficiency and selectivity.
In the synthesis of Methyl Prednisolone, 4,4,4-TriMethoxybutanoic Acid Methyl Ester serves as a valuable building block, providing the necessary structural elements and functional groups required for the formation of the final product. Its use in this application highlights its importance in the pharmaceutical industry, where it contributes to the development of life-saving medications and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 71235-00-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,2,3 and 5 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 71235-00:
(7*7)+(6*1)+(5*2)+(4*3)+(3*5)+(2*0)+(1*0)=92
92 % 10 = 2
So 71235-00-2 is a valid CAS Registry Number.
71235-00-2Relevant articles and documents
Synthesis and evaluation of antiinflammatory activities of a series of corticosteroid 17α-esters containing a functional group
Ueno,Maruyama,Miyake,Nakao,Nakao,Umezu,Nitta
, p. 2468 - 2473 (2007/10/02)
A series of 21-desoxy-21-chlorocorticosteroids that contain a functionalized ester group at 17α has been prepared and examined to separate their systemic activity from topical antiinflammatory activity. Introduction of the functionalized ester group at 17α was carried out by an acid-catalyzed formation of cyclic ortho esters with 17α,21-hydroxyl groups of corticosteroids and subsequent acid-catalyzed hydrolysis. As for the functional group, chloro, methoxy, acetoxy, cyano, cyclopropyl, or alkoxycarbonyl group was introduced at the terminal carbon atom of the 17α-alkanoate group. The topical antiinflammatory activity and systemic activity of these compounds were examined and found to be signficantly dependent on the functionalities in the 17α-esters. Among these derivatives, a series of 17α-(alkoxycarbonyl)alkanoates (17α-OCO(CH2)(n)COOR) showed an excellent separation of the systemic activity from topical activity. The effects of the number of methylene groups (n) and of the alkyl groups of the ester (R) on either topical or systemic activity of the corticosteroid derivatives were also investigated.
