71235-92-2

Basic information

• Product Name: 1-METHYLPIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE
• Synonyms: BIO-FARMA BF002150;1-METHYL-PIPERIDINE-4-CARBOXYLIC ACID HCL;1-METHYLPIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE;1-METHYLPIPERIDINO-4-CARBOXYLIC ACID HYDROCHLORIDE;1-METHYL-4-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE;4-CARBOXY-1-METHYL-PIPERIDINE HCL;RARECHEM AH CK 0139;TIMTEC-BB SBB003751
• CAS NO: 71235-92-2
• Molecular Formula: C7H14ClNO2
• Molecular Weight: 179.64
• Mol File: 71235-92-2.mol
• Article Data: 7

Chemical Properties

• Melting Point: 234-235°C
• Boiling Point: 246.1 °C at 760 mmHg
• Flash Point: 102.6 °C
• Appearance: /
• Vapor Pressure: 0.00899mmHg at 25°C
• CAS DataBase Reference: 1-METHYLPIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYLPIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE(71235-92-2)
• EPA Substance Registry System: 1-METHYLPIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE(71235-92-2)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-41
• Safety Statements: 26-39
• HazardClass: IRRITANT
• Hazardous Substances Data: 71235-92-2(Hazardous Substances Data)

Usage

General Description

1-Methylpiperidine-4-carboxylic acid hydrochloride is a chemical compound that is a derivative of piperidine, a six-membered nitrogen-containing heterocycle. It is a hydrochloride salt of 1-methylpiperidine-4-carboxylic acid, and is used as a building block in the synthesis of various pharmaceuticals and organic compounds. It is known for its diverse applications in drug development and chemical research, and its hydrochloride form makes it more stable and soluble in water, which is advantageous for its various uses. The compound is also known for its potential as a starting material for the synthesis of new drugs due to its unique structural features and functional groups.

InChI:InChI=1/C7H13NO2.ClH/c1-8-4-2-6(3-5-8)7(9)10;/h6H,2-5H2,1H3,(H,9,10);1H

Upstream product

• 498-94-2 isonipecotic acid 
• 50-00-0 formaldehyd 
• 24252-37-7 ethyl 1-methylisonipecotate 

Downstream Products

• 50675-21-3 N-methyl-piperidine-4-carboxaldehyde 

Relevant articles and documents

PROCESSES AND INTERMEDIATE FOR THE LARGE-SCALE PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-YL]-BENZAMIDE HEMISUCCINATE, AND PREPARATION OF 2,4,6-TRIFLUORO-N-[6-(1-METHYL-PIPERIDINE-4-CARBONYL)-PYRIDIN-2-YL]-BENZAMIDE ACE

The embodiments of present invention provide processes and an intermediate for the large-scale preparation of 2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridyl]benzamide hemisuccinate, and formulations and product forms made by these processe

COMPOSITIONS AND METHODS OF SYNTHESIS OF PYRIDINOYLPIPERIDINE 5-HT1F AGONISTS

The present invention provides a novel polymorph of the hemisuccinate salt of 2,4,6-trifluoro-N-[6-(1-methyl-piperidine-4-carbonyl)-pyridin-2-yl]-benzamide (Form A) characterized by a unique X-ray diffraction pattern and Differential Scanning Calorimetry

Pyrrole derivatives, their preparation and pharmaceutical compositions which contain them

This invention relates to pyrrole derivatives of formula: STR1 in which A forms with the pyrrole ring an isoindoline, 6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine, 2,3,6,7-tetrahydro-5H-[1,4]oxathiino[2,3-c]pyrrole or 2,3,6,7-tetrahydro-5H-[1,4]dithiino[2,3-c]pyrrole ring-system and Hetis naphthyridinyl, pyridyl or quinolyl which is unsubstituted or substituted with halogen, (1 to 4 C) alkyl, (1 to 4 C) alkyloxy, (1 to 4 C) alkylthio or CF3 and R=(3 to 10 C) straight- or branched-chain alkenyl or alkyl which is unsubstituted or substituted with alkyloxy, alkylthio, (3 to 6 C) cycloalkyl, NH2, alkylamino, dialkylamino, alkylcarbonylamino, (in which the amino portion is optionally substituted with alkyl), 1- or 2-piperazinyl, piperidyl, piperidino, morpholino, pyrrolidinyl, 1-azetidinyl, carbamoyl, alkylcarbamoyl, dialkylcarbamoyl, (1-piperazinyl)carbonyl, piperidinocarbonyl, (1-pyrrolidinyl)carbonyl, phenyl, pyridyl, 1-imidazolyl, or alternatively R=2- or 3-pyrrolidinyl, 2-, 3- or 4-piperidyl, on the understanding that the alkyl radicals are straight- or branched-chain radicals and contain, except where specifically stated, 1 to 10 C, and that the piperazinyl, piperidino, piperidyl, pyrrolidinyl and azetidinyl radicals can be unsubstituted or substituted at any position with alkyl, alkylcarbonyl, benzyl or hydroxyalkyl, or can alternatively form a lactam group with the nitrogen atom of the ring, and, where they exist, their pharmaceutically acceptable salts and optical isomers, are useful as anxiolytics.