71315-63-4

Basic information

• Product Name: Benzoic acid 2-(p-bromophenyl)hydrazide
• Synonyms: Benzoic acid 2-(p-bromophenyl)hydrazide
• CAS NO: 71315-63-4
• Molecular Formula: C₁₃H₁₁BrN₂O
• Molecular Weight: 291.14324
• Mol File: 71315-63-4.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid 2-(p-bromophenyl)hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid 2-(p-bromophenyl)hydrazide(71315-63-4)
• EPA Substance Registry System: Benzoic acid 2-(p-bromophenyl)hydrazide(71315-63-4)

Safety Data

• Hazardous Substances Data: 71315-63-4(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 108574-21-6 N-(4-bromophenyl)-N'-benzoyldiazene 
• 861568-79-8 benzoic acid-[N'-(4-bromo-phenyl)-N'-nitroso-hydrazide] 
• 98-88-4 benzoyl chloride 
• 589-21-9 (4-bromophenyl)hydrazine 
• 60-29-7 diethyl ether 
• 100-63-0 phenylhydrazine 
• 532-96-7 N-benzoyl-N'-phenylhydrazine 
• 110-86-1 pyridine 
• 72437-42-4 [(4-bromophenyl)diazenyl](phenyl)methyl hydroperoxide 
• 110-83-8 cyclohexene 
• 7726-95-6 bromine 
• 622-88-8 4-bromophenylhydrazine hydrochloride 
• 65-85-0 benzoic acid 

Downstream Products

• 39209-23-9 N',N'-bis(4-bromophenyl)benzohydrazide 
• 108574-21-6 N-(4-bromophenyl)-N'-benzoyldiazene 
• 861568-79-8 benzoic acid-[N'-(4-bromo-phenyl)-N'-nitroso-hydrazide] 
• 857816-02-5 N'-benzoyl-N-(4-bromo-phenyl)-N-chloroacetyl-hydrazine 
• 41626-19-1 chloro(phenyl)methanone p-bromophenylhydrazone 
• 106-39-8 bromochlorobenzene 
• 1426854-85-4 1-(4-bromophenyl)-1H-indazol-3-amine 
• 108574-21-6 (E)-((4-bromophenyl)diazenyl)(phenyl)methanone 

Relevant articles and documents

A [4 + 3] Annulation Reaction of aza- o-Quinone Methides with Arylcarbohydrazonoyl Chlorides for Synthesis of 2,3-Dihydro-1 H-benzo[ e][1,2,4]triazepines

An unprecedented [4 + 3] annulation reaction of aza-ortho-quinone methides with arylcarbohydrazonoyl chlorides has been achieved under mild conditions. The annulation underwent a sequential conjugate addition/intramolecular annulation/rearrangement, providing a useful method for the synthesis of biologically interesting 2,3-dihydro-1H-benzo[e][1,2,4]triazepine.

Easy and rapid preparation of benzoylhydrazides and their diazene derivatives as inhibitors of 15-lipoxygenase

Two series of diaza derivatives were prepared by solvent-free condensation of benzoic acid and 4-substituted phenylhydrazines in order to obtain phenylhydrazides (HYD series) and, by oxidation of these compounds, the corresponding benzoyldiazenes (DIA series). Both sets were evaluated as inhibitors of soybean 15-lipoxygenase activity and antioxidant capability in the FRAP and CUPRAC assays. The most potent inhibitors of both series exhibited IC50 values in the low micromolar range. Kinetic studies showed that at least the more active compounds were competitive inhibitors. Docking results indicated that the most potent inhibitor interacts strongly with Ile-839 and iron in the active site.

KOt-Bu promoted homocoupling and decomposition of N'-aryl acylhydrazines: synthesis of unsymmetric N',N'-diaryl acylhydrazines

The KOt-Bu promoted homocoupling and decomposition of N'-aryl acylhydrazines has been achieved. The method allows for a novel and efficient synthesis of unsymmetric N',N'-diaryl acylhydrazines under mild reaction conditions. The reaction probably proceeds via the generation of N'-centered acylhydrazine radicals and the subsequent homolytic aromatic substitution.