71420-92-3 Usage
Description
4-BOC-AMINOMETHYLPHENYLACETIC ACID, also known as 4-(tert-Butoxycarbonylamino)methylphenylacetic acid, is an organic compound with a solid chemical structure. It is characterized by its unique molecular composition, which includes a phenyl ring, an acetic acid group, and a protected aminomethyl group. 4-BOC-AMINOMETHYLPHENYLACETIC ACID is known for its role in the synthesis of various pharmaceutical agents and its potential applications in the medical field.
Uses
Used in Pharmaceutical Synthesis:
4-BOC-AMINOMETHYLPHENYLACETIC ACID is used as a key intermediate in the synthesis of glycine-site N-methyl-D-aspartate (NMDA) antagonists. These antagonists possess anticonvulsant activities and are crucial in the development of treatments for epilepsy and other seizure disorders. 4-BOC-AMINOMETHYLPHENYLACETIC ACID's unique structure allows for the creation of molecules that can effectively target and modulate the NMDA receptor, providing a promising avenue for the development of novel therapeutic agents.
Used in Inhibitor Development:
In the field of enzyme inhibition, 4-BOC-AMINOMETHYLPHENYLACETIC ACID is utilized to prepare potent dipeptide inhibitors of the pp60c-src SH2 domain. The pp60c-src is a non-receptor tyrosine kinase that plays a significant role in various cellular processes, including cell growth, differentiation, and transformation. Inhibiting the pp60c-src SH2 domain can help regulate these processes and potentially lead to the development of treatments for various diseases, such as cancer.
Used in Chemical Research:
Due to its unique chemical properties and structure, 4-BOC-AMINOMETHYLPHENYLACETIC ACID is also used in chemical research as a building block for the synthesis of various organic compounds. Researchers can use this compound to explore new reaction pathways, develop novel synthetic methods, and create innovative molecules with potential applications in various industries, including pharmaceuticals, materials science, and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 71420-92-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,4,2 and 0 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 71420-92:
(7*7)+(6*1)+(5*4)+(4*2)+(3*0)+(2*9)+(1*2)=103
103 % 10 = 3
So 71420-92-3 is a valid CAS Registry Number.
71420-92-3Relevant articles and documents
HETEROARYL-CARBOXYLIC ACIDS AS HISTONE DEMETHYLASE INHIBITORS
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Page/Page column 131; 132, (2018/01/17)
The invention relates to heteroaryl-carboxylic acids as described herein, useful as histone demethylase inhibitors. The invention also relates to pharmaceutical compositions comprising these compounds and to their use in therapy, including e.g., in the treatment of cancer.
HETEROCYCLIC COMPOUND AND HEMATOPOIETIC STEM CELL AMPLIFIER
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Page/Page column 60, (2012/04/23)
An expansion agent for hematopoietic stem cells and/or hematopoietic progenitor cells useful for improvement in the efficiency of gene transfer into hematopoietic stem cells for gene therapy useful for treatment of various disorders is provided. An expansion agent for hematopoietic stem cells and/or hematopoietic progenitor cells containing a compound represented by the formula (I) (wherein X, Y, Z, Ar1, R1, R2, R3, R4, R5, R6 and R7 are as defined in the description), a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof, which can expand hematopoietic stem cells and/or hematopoietic progenitor cells.
4,6-DISUBSTITUTED PYRIMIDINES AND THEIR USE AS PROTEIN KINASE INHIBITORS
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Page/Page column 55, (2008/06/13)
The invention relates to novel pyrimidine derivatives of Formula (I), which are efficacious inhibitors of protein kinases, in particular of one or more isoforms of the protein kinase B/Akt.
