71443-22-6Relevant articles and documents
Expeditious metal-free access to functionalized polycyclic acetals under mild aqueous conditions
Kasare, Sanghratna,Bankar, Siddheshwar K.,Ramasastry
, p. 4284 - 4287 (2014)
A facile approach for the synthesis of furopyrans and bicyclic bisacetals under mild aqueous conditions is described. This potentially green, diversity oriented approach involves cascade Michael addition and cycloacetalization of pyranones and 1,3-dicarbo
Palladium-Catalyzed [3 + 2]-C-C/N-C Bond-Forming Annulation
Liu, Yang,Mao, Zhongyi,Pradal, Alexandre,Huang, Pei-Qiang,Oble, Julie,Poli, Giovanni
supporting information, p. 4057 - 4061 (2018/07/15)
The synthesis of bi- and tricyclic structures incorporating pyrrolidone rings is disclosed, starting from resonance-stabilized acetamides and cyclic α,β-unsaturated-γ-oxycarbonyl derivatives. This process involves an intermolecular Tsuji-Trost allylation/intramolecular nitrogen 1,4-addition sequence. Crucial for the success of this bis-nucleophile/bis-electrophile [3 + 2] annulation is its well-defined step chronology in combination with the total chemoselectivity of the former step. When the newly formed annulation product carries a properly located o-haloaryl moiety at the nitrogen substituent, a further intramolecular keto α-arylation can join the cascade, thereby forming two new cycles and three new bonds in the same synthetic operation.
The Intramolecular Enyne Diels-Alder Reaction. Stereoselective Construction of Tricyclic Dioxadienones and Mechanistic Outline
Hoffmann, H. M. R.,Krumwiede, D.,Mucha, B.,Oehlerking, H. H.,Prahst, G. W.
, p. 8999 - 9018 (2007/10/02)
4-Methylpent-4-en-2-yn-1-ols and 6-hydroxy-2,3-dihydro-6H-pyran-3-ones are condensed in different ways to a series of tricyclic dioxadienones which contain the basic framework of the cadlinolides A mechanism of the intramolecular enyne-ene cycloisomerization and the origin of the resulting type I and type II dienes is proposed.
