71444-29-6Relevant articles and documents
A highly asymmetric direct aldol reaction catalyzed by chiral proline amide-thiourea bifunctional catalysts
Li, Yun,Yang, Qing-Chuan,Xu, Xiao-Ying,Zhou, Yong,Bai, Jian-Fei,Wang, Fei-Ying,Wang, Li-Xin
, p. 1312 - 1318 (2011)
A series of chiral proline amide-thiourea bifunctional catalysts derived from l-proline and chiral diamine were prepared and successfully applied to highly enantioselective direct aldol reactions of cyclohexanone with various aldehydes in excellent yields
Consequences of folding a water-soluble polymer around an organocatalyst
Huerta, Elisa,Stals, Patrick J. M.,Meijer,Palmans, Anja R. A.
, p. 2906 - 2910 (2013)
Give'em structure: The presence of structuring elements in polymers that were functionalized with catalytic units resulted in a new class of enzyme mimics, which are only active in the folded state (see picture). The conformationally adaptive hydrophobic
Asymmetric aldol reaction on water using an organocatalyst tethered on a thermoresponsive block copolymer
Suzuki, Noriyuki,Inoue, Takahiro,Asada, Takumi,Akebi, Ryuji,Kobayashi, Go,Rikukawa, Masahiro,Masuyama, Yoshiro,Ogasawara, Masamichi,Takahashi, Tamotsu,Thang, San H.
, p. 1493 - 1495 (2013)
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A chemo-enzymatic oxidation/aldol sequential process directly converts arylbenzyl alcohols and cyclohexanol into chiral β-hydroxy carbonyls
Cheng, Qipeng,Li, Hongyu,Liu, Guohua,Su, Yu,Tan, Chunxia,Wang, Chengyi,Wang, Yu,Xiao, Rui
supporting information, p. 7773 - 7779 (2021/10/12)
The development of a combination enzyme and organocatalyst for aqueous sequential organic transformation has great significance, in that it is not only environmentally friendly but also overcomes only a single methodological drawback, either in the chemical or biological process. Herein, through the utilization of the bulky steric hindrance of chiral proline derivatives, an integrated laccase and proline as a chemo-enzymatic co-catalyst system is developed. It enables an efficient oxidation/aldol enantioselective sequential reaction to be accomplished, overcoming the mutual deactivation issue. As we present in this study, this one-pot organic transformation, an initial laccase-mediated oxidation of arylbenzyl alcohols and cyclohexanol to form aldehydes and cyclohexanone, followed by a subsequent proline derivative-catalyzed aldol condensation of the in situ generated intermediates, provides various 1,2-diastereoisomeric chiral β-hydroxy ketones with acceptable yields and high enantio-/diastereoselectivities.
Biomass waste-derived recyclable heterogeneous catalyst for aqueous aldol reaction and depolymerization of PET waste
Khiangte, Vanlalngaihawma,Laldinpuii, Z. T.,Lalhmangaihzuala, Samson,Lalmuanpuia, Chhakchhuak,Pachuau, Zodinpuia,Vanlaldinpuia, Khiangte
, p. 19542 - 19552 (2021/11/09)
In this work, we discuss the valorization of biomass waste-derived orange peel ash (OPA) by exploring its applicability as a heterogeneous catalyst in aqueous aldol reactions and demonstrating its versatility by promoting the methanolysis of poly(ethylene terephthalate) (PET) waste. The catalyst was characterized using Fourier-transform infrared spectroscopy (FT-IR), Brunauer-Emmett-Teller (BET) analysis, X-ray powder diffraction (XRD), X-ray fluorescence (XRF), energy dispersive X-ray (EDX) spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and thermal gravimetric analysis (TGA) to decode its chemical composition. The aldol reactions were carried out at ambient temperature in the presence of water as a solvent. PET depolymerization was performed in an autoclave for 1 h using only 6% w/w OPA. The catalyst was recovered and reused in both the reactions for up to four successive cycles with minimal loss in the catalytic activity. The use of OPA as a cost-free, eco-friendly and effective recyclable catalyst enables a greener route for C-C bond formation and PET waste recycling.