7145-49-5

Basic information

• Product Name: 3-Methoxy-5-nitrophenol
• Synonyms: 3-Methoxy-5-nitrophenol
• CAS NO: 7145-49-5
• Molecular Formula: C₇H₇NO₄
• Molecular Weight: 169.13478
• Mol File: 7145-49-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 340.4°Cat760mmHg
• Flash Point: 159.7°C
• Appearance: /
• Density: 1.367g/cm³
• Vapor Pressure: 4.37E-05mmHg at 25°C
• Refractive Index: 1.583
• Storage Temp.: 2-8°C
• PKA: 7.96±0.10(Predicted)
• CAS DataBase Reference: 3-Methoxy-5-nitrophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methoxy-5-nitrophenol(7145-49-5)
• EPA Substance Registry System: 3-Methoxy-5-nitrophenol(7145-49-5)

Safety Data

• Hazardous Substances Data: 7145-49-5(Hazardous Substances Data)

Usage

Properties

1. Chemical Name: 3-Methoxy-5-nitrophenol
2. Appearance: Yellow crystalline
3. Solubility: Insoluble in water, soluble in organic solvents
4. Odor: Mild, sweet
5. Toxicity: Moderately toxic

Specific Content

1. Nitro group and methoxy group attached to a phenol ring
2. Commonly used as a starting material in the synthesis of pharmaceuticals and agrochemicals
3. Used in the manufacture of dyes, perfumes, and flavoring agents
4. Can cause irritation to the skin, eyes, and respiratory system upon contact or inhalation.

InChI:InChI=1/C7H7NO4/c1-12-7-3-5(8(10)11)2-6(9)4-7/h2-4,9H,1H3

Upstream product

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Downstream Products

• 20734-70-7 5-nitroresorcinol 
• 13831-58-8 dimethyl-carbamic acid-(3-hydroxy-5-nitro-phenyl ester) 
• 93042-59-2 1,3-bis-dimethylcarbamoyloxy-5-nitro-benzene 
• 13944-86-0 1-dimethylcarbamoyloxy-3-nitro-5-[3-(3-nitro-phenoxy)-propoxy]-benzene 
• 20734-67-2 3,5-dihydroxyphenylamine 
• 855426-08-3 1,3-bis-(3-dimethylcarbamoyloxy-5-nitro-phenoxy)-propane 
• 1098619-23-8 3-[(3,5-dichlorophenyl)methoxy]-4-methoxyphenylamine 
• 880882-06-4 3-(3-methoxy-5-nitrophenoxy)tetrahydrofuran 
• 1610450-73-1 2-(2-(2-(3-methoxy-5-nitrophenoxy)ethoxy)ethoxy)ethanol 
• 1610449-42-7 1-(4-((2-((3-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)-5-methoxyphenyl)amino)pyrimidin-4-yl)oxy)naphthalen-1-yl)-3-(3-isopropyl-1-(p-tolyl)-1H-pyrazol-5-yl)urea 
• 1610450-20-8 2-(2-(2-(3-amino-5-methoxyphenoxy)ethoxy)ethoxy)ethanol 
• 1610449-86-9 1-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(4-((2-((3-(2-(2-(2-(dimethylamino)ethoxy)ethoxy)ethoxy)-5-methoxyphenyl)amino)pyrimidin-4-yl)oxy)naphthalen-1-yl)urea 
• 1610450-60-6 3-(2-(2-(2-(dimethylamino)ethoxy)ethoxy)ethoxy)-5-methoxyaniline 
• 1610449-88-1 1-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(4-((2-((3-methoxy-5-(2-(2-(2-morpholinoethoxy)ethoxy)ethoxy)phenyl)amino)pyrimidin-4-yl)oxy)naphthalen-1-yl)urea 

Relevant articles and documents

IRAK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

UREA DERIVATIVES USEFUL AS KINASE INHIBITORS

There are provided compounds of formula I, wherein R1, R1A, R1C to R1E, Ra, Rb, X1, E and G have meanings given in the description, which compounds have antiinflammatory activity (e.g. through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes; Syk kinase; and members of the Src family of tyrosine kinases) and have use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.

UREA DERIVATIVES USEFUL AS KINASE INHIBITORS

There are provided compounds of formula I, wherein R1A to R1E, R2 to R5, L and X1 to X3 have meanings given in the description, which compounds have antiinflammatory activity (e.g. through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes; Syk kinase; and members of the Src family of tyrosine kinases) and have use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.