71475-35-9

Basic information

• Product Name: Lozilurea
• Synonyms: Lozilurea;1-(3-chlorobenzyl)-3-ethyl-urea;1-[(3-chlorophenyl)methyl]-3-ethylurea;1-[(3-chlorophenyl)methyl]-3-ethyl-urea
• CAS NO: 71475-35-9
• Molecular Formula: C10H13ClN2O
• Molecular Weight: 212.679
• Mol File: 71475-35-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 404.2°C at 760 mmHg
• Flash Point: 198.2°C
• Appearance: /
• Density: 1.2426 (rough estimate)
• Vapor Pressure: 9.64E-07mmHg at 25°C
• Refractive Index: 1.6000 (estimate)
• CAS DataBase Reference: Lozilurea(CAS DataBase Reference)
• NIST Chemistry Reference: Lozilurea(71475-35-9)
• EPA Substance Registry System: Lozilurea(71475-35-9)

Safety Data

• Hazardous Substances Data: 71475-35-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H13ClN2O/c1-2-12-10(14)13-7-8-4-3-5-9(11)6-8/h3-6H,2,7H2,1H3,(H2,12,13,14)

Upstream product

• 14467-72-2 ethyl-thiocarbamic acid S-(4-chloro-phenyl) ester 
• 4152-90-3 m-chlorobenzylamine 
• 815582-19-5 ethyl-thiocarbamic acid S-p-tolyl ester 
• 815582-22-0 ethyl-thiocarbamic acid S-(4-bromo-phenyl) ester 
• 14467-74-4 S-phenyl N-ethylthiocarbamate 

Relevant articles and documents

Kinetics and mechanism of the aminolysis of aryl N-ethyl thiocarbamates in acetonitrile

The aminolysis of aryl N-ethyl thiocarbamates (EtNHC(=O)SC 6H4Z) with benzylamines (XC6H 4-CN2NH2) in acetonitrile at 30.0 °C is investigated. The rates are faster than the corresponding values for aryl N-phenyl thiocarbamates (PhNHC(=O)SC6H4Z), reflecting a stronger push to expel the leaving group by EtNH than the PhNH nonleaving group in a concerted process. The negative ρXZ (-0.86) and failure of the reactivity-selectivity principle found are consistent with the concerted mechanism. The kinetic isotope effects involving deuterated nucleophiles (k H/kD = 1-5-1.7) and low ΔH? with large negative ΔS? values suggest a hydrogen bond cyclic transition state.