714973-96-3

Basic information

• Product Name: (2S,4R,8S,Z)-9-(tert-butyldiphenylsilyloxy)-2,4,6,8-tetramethylnon-3-en-1-ol
• Synonyms: (2S,4R,8S,Z)-9-(tert-butyldiphenylsilyloxy)-2,4,6,8-tetramethylnon-3-en-1-ol
• CAS NO: 714973-96-3
• Molecular Weight: 452.753
• Mol File: 714973-96-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,4R,8S,Z)-9-(tert-butyldiphenylsilyloxy)-2,4,6,8-tetramethylnon-3-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4R,8S,Z)-9-(tert-butyldiphenylsilyloxy)-2,4,6,8-tetramethylnon-3-en-1-ol(714973-96-3)
• EPA Substance Registry System: (2S,4R,8S,Z)-9-(tert-butyldiphenylsilyloxy)-2,4,6,8-tetramethylnon-3-en-1-ol(714973-96-3)

Safety Data

• Hazardous Substances Data: 714973-96-3(Hazardous Substances Data)

Upstream product

• 75-24-1 trimethylaluminum 
• 714973-95-2 (2S,6R,8S)-9-(tert-butyldiphenylsilyloxy)-2,6,8-trimethylnon-3-yn-1-ol 
• 147782-80-7 (2S,4R)-5-(tert-butyl(dimethyl)silyloxy)-2,4-dimethyl-1-pentanol 
• 714974-22-8 C₁₃H₃₀SiO₂SiC₁₆H₁₈ 
• 335060-49-6 (2S,4R)-5-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-2,4-dimethylpentyl acetate 
• 157837-65-5 (2R,4S)-5-{[tert-butyl(diphenyl)silyl]oxy}-2,4-dimethylpentanal 
• 157837-64-4 (2R,4S)-5-{[tert-butyl(diphenyl)silyl]oxy}-2,4-dimethylpentan-1-ol 
• 90270-02-3 (2R,4S)-1-hydroxy-2,4-dimethylpentyl acetate 

Downstream Products

• 714973-97-4 (-)-(2S,4R,6S,8S)-9-(tert-butyl-diphenyl-silyloxy)-2,4,6,8-tetramethyl-nonan-1-ol 
• 935872-45-0 (3S,4S,6S,8R,10S)-((S,3E,5Z)-6-bromo-6-cyano-1-{(1R,2R)-2-[(4-methoxybenzyloxy)methyl]cyclopentyl}hexa-3,5-dienyl) 3-(tert-butyldimethylsilyloxy)-4,6,8,10-tetramethyl-11-(tetrahydro-2H-pyran-2-yloxy)undecanoate 
• 935872-49-4 (3S,4S,6S,8R,10S)-((S,3E,5Z)-6-bromo-6-cyano-1-{(1R,2R)-2-[(4-methoxybenzyloxy)methyl]cyclopentyl}hexa-3,5-dienyl) 3-(tert-butyldimethylsilyloxy)-11-hydroxy-4,6,8,10-tetramethylundecanoate 
• 935872-55-2 C₄₂H₆₆O₆SiNCOCF₃ 
• 935872-03-0 (3S,4S,6S,8R,10S)-((S,3E,5Z)-7-allyloxy-6-bromo-1-{(1R,2R)-2-[(4-methoxybenzyloxy)methyl]cyclopentyl}-7-oxohepta-3,5-dienyl) 3-(tert-butyldimethylsilyloxy)-4,6,8,10-tetramethyl-11-oxoundecanoate 
• 935872-06-3 (3S,4S,6S,8R,10S)-((S,3E,5Z)-7-(allyloxy)-6-bromo-1-{(1R,2R)-2-[(4-methoxybenzyloxy)methyl]cyclopentyl}-7-oxohepta-3,5-dienyl) 3-(tert-butyldimethylsilyloxy)-4,6,8,10-tetramethyl-11-(tetrahydro-2H-pyran-2-yloxy)undecanoate 
• 935872-07-4 (3S,4S,6S,8R,10S)-((S,3E,5Z)-7-(allyloxy)-6-bromo-1-{(1R,2R)-2-[(4-methoxybenzyloxy)methyl]cyclopentyl}-7-oxohepta-3,5-dienyl) 3-(tert-butyldimethylsilyloxy)-11-hydroxy-4,6,8,10-tetramethylundecanoate 
• 935872-09-6 (2S,4E,6E,8S,9S,11R,13S,15S,16S)-allyl 16-(tert-butyldimethylsilyloxy)-8-hydroxy-2-{(1R,2R)-2-[(4-methoxybenzyloxy)methyl]cyclopentyl}-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-diene-7-carboxylate 
• 935872-10-9 (2S,4E,6E,8S,9S,11R,13S,15S,16S)-allyl 8,16-bis(tert-butyldimethylsilyloxy)-2-{(1R,2R)-2-[(4-methoxybenzyloxy)methyl]cyclopentyl}-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-diene-7-carboxylate 
• 935872-12-1 (2S,4E,6E,8S,9S,11R,13S,15S,16S)-16-(tert-butyldimethylsilyloxy)-2-{(1R,2R)-2-[(4-methoxybenzyloxy)methyl]cyclopentyl}-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-diene-7-carboxylic acid 
• 935872-13-2 (2S,4E,6E,8S,9S,11R,13S,15S,16S)-16-(tert-butyldimethylsilyloxy)-2-{(1R,2R)-2-[(4-methoxybenzyloxy)methyl]cyclopentyl}-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-diene-7-carboxamide 
• 7184-60-3 borrelidin 
• 714974-18-2 (1''S,1'''R,2'''R,3S,4S,6S,8R,10S)-3-(tert-butyldimethyl-silyloxy)-4,6,8,10-tetramethyl-11-(tetrahydropyran-2'-yloxy)undecanoic acid 6''-bromo-6''-cyano-1-[2'''-(4'''-methoxymenzyloxymethyl)cyclopentyl]hexa-3''E,5''E-dienyl ester 
• 714974-20-6 (1'R,2S,2'R,8R,9S,11R,13S,15S,16S)-9,16-bis(tert-butyldimethylsilyloxy)-2-[2'-(4''-methoxybenzyloxymethyl)cyclopentyl]-9,11,13,15-tetramethyl-18-oxo-oxaoctadeca-4E,6Z-diene-7-carbonitrile 

Relevant articles and documents

Total synthesis of borrelidin

(Chemical Equation Presented) The total synthesis of borrelidin has been achieved. The best feature of our synthetic route is macrocyclization at C11-C12 for the construction of an 18-membered ring after esterification between two segments. A detailed examination of the macrocyclization led us to the samarium(II) iodide-mediated intramolecular Reformatsky-type reaction as the most efficient synthetic approach. The two key segments were synthesized through regioselective methylation, directed hydrogenation, stereoselective Reformatsky-type reaction, and MgBr2·Et2O-mediated chelation-controlled allylation.