71628-89-2

Basic information

• Product Name: (1S,3S)-3-acetyl-2,2-dimethylcyclobutaneacetaldehyde1,6-cyclodecanedione
• Synonyms: (1S,3S)-3-acetyl-2,2-dimethylcyclobutaneacetaldehyde1,6-cyclodecanedione
• CAS NO: 71628-89-2
• Molecular Weight: 168.236
• Mol File: 71628-89-2.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: (1S,3S)-3-acetyl-2,2-dimethylcyclobutaneacetaldehyde1,6-cyclodecanedione(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,3S)-3-acetyl-2,2-dimethylcyclobutaneacetaldehyde1,6-cyclodecanedione(71628-89-2)
• EPA Substance Registry System: (1S,3S)-3-acetyl-2,2-dimethylcyclobutaneacetaldehyde1,6-cyclodecanedione(71628-89-2)

Safety Data

• Hazardous Substances Data: 71628-89-2(Hazardous Substances Data)

Upstream product

• 71582-32-6 1-((1S,3S)-3-(2,2-dimethoxyethyl)-2,2-dimethylcyclobutyl)ethan-1-one 
• 17879-35-5 cis-pinonic acid 
• 22630-96-2 1-(2-Hydroxyethyl)-3-(1-hydroxyethyl)-2,2-dimethylcyclobutane 
• 80-56-8 Pinene 
• 80-56-8 rac-α-pinene 
• 21803-49-6 (1S,2S,3R,5S)-(+)-pinanediol 
• 18680-27-8 pinanediol 
• 129222-66-8 C₆H₇(CH₂)(OOSn(C₄H₉)3)(C(CH₃)2) 
• 7785-70-8 (+)-α-pinene 

Downstream Products

• 177316-73-3 1-((1S)-2,2,3c-trimethyl-cyclobut-r-yl)-ethanone 
• 132478-08-1 cis-pinononic aldehyde 
• 22571-78-4 (+)-cis-pinononoic acid 
• 28465-10-3 (+)-(1R)-cis-2,2-dimethyl-3-isopropenylcyclobutanemethanol acetate 
• 92469-61-9 6-(2,2,3-trimethyl-cyclobutyl)-hepta-3,5-dien-2-one 
• 2704-79-2 1-(2,2,3-trimethyl-cyclobutyl)-ethanone 

Relevant articles and documents

Synthesis and Inhibitory Properties of Imines Containing Monoterpenoid and Adamantane Fragments Against DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1 (Tdp1)

Six imines including four new ones were synthesized via the reaction of monoterpenoid aldehydes with aminoadamantanes. The inhibitory activities of the synthesized compounds against purified human recombinant DNA repair enzyme tyrosyl-DNA phosphodiesterase 1 (Tdp1) fell in the range IC50 = 5.5–7.1 μM.

Molecular Chirality and Cloud Activation Potentials of Dimeric α-Pinene Oxidation Products

The surface activity of ten atmospherically relevant α-pinene-derived dimers having varying terminal functional groups and backbone stereochemistry is reported. We find ～10% differences in surface activity between diastereomers of the same dimer, demonstrating that surface activity depends upon backbone stereochemistry. Octanol-water (KOW) and octanol-ammonium sulfate partitioning coefficient (KOAS) measurements of our standards align well with the surface activity measurements, with the more surface-active dimers exhibiting increased hydrophobicity. Our findings establish a link between molecular chirality and cloud activation potential of secondary organic aerosol particles. Given the diurnal variations in enantiomeric excess of biogenic emissions, possible contributions of such a link to biosphere:atmosphere feedbacks as well as aerosol particle viscosity and phase separation are discussed.

Dibismuthanes in catalysis: From synthesis and characterization to redox behavior towards oxidative cleavage of 1,2-diols

A family of aryl dinuclear bismuthane complexes has been successfully synthesized and characterized. The two bismuth centers are bonded to various xanthene-type backbones, which differ in ring-size and flexibility, resulting in complexes with different intramolecular Bi?Bi distances. Moreover, their pentavalent Bi(v) analogues have also been prepared and structurally characterized. Finally, the synergy between bismuth centers in catalysis has been studied by applying dinuclear bismuthanes5-8to the catalytic oxidative cleavage of 1,2-diols. Unfortunately, no synergistic effects were observed and the catalytic activities of dinuclear bismuthanes and triphenylbismuth are comparable.

Nickel-Catalyzed Selective Reduction of Carboxylic Acids to Aldehydes

The direct reduction of carboxylic acids to aldehydes is a fundamental transformation in organic synthesis. The combination of an air-stable Ni precatalyst, dimethyl dicarbonate as an activator, and silane reductant effects this reduction for a wide variety of substrates, including pharmaceutically relevant structures, in good yields and with no overreduction to alcohols. Moreover, this methodology is scalable, allows access to deuterated aldehydes, and is also compatible with one-pot utilization of the aldehyde products.