71644-60-5

Basic information

• Product Name: 3,4-diphenyl-2H-1-benzopyran-2-one
• Synonyms: 3,4-diphenyl-2H-1-benzopyran-2-one
• CAS NO: 71644-60-5
• Molecular Weight: 298.341
• Mol File: 71644-60-5.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: 3,4-diphenyl-2H-1-benzopyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-diphenyl-2H-1-benzopyran-2-one(71644-60-5)
• EPA Substance Registry System: 3,4-diphenyl-2H-1-benzopyran-2-one(71644-60-5)

Safety Data

• Hazardous Substances Data: 71644-60-5(Hazardous Substances Data)

Upstream product

• 117-99-7 2-Hydroxybenzophenone 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 1333483-14-9 N-methyll-N-(phenylethylnyl)methanesulfonamide 
• 766-82-5 1-ethynyl-3-methyl-benzene 
• 201230-82-2 carbon monoxide 
• 5661-50-7 N-(phenoxy)acetamide 
• 501-65-5 diphenyl acetylene 
• 100954-03-8 phenyl 3-phenylprop-2-ynoate 
• 66003-76-7 Diphenyliodonium triflate 
• 637-44-5 phenylpropyolic acid 
• 108-95-2 phenol 
• 24486-06-4 O-phenyl-N,N-diethyl thiocarbamate 
• 16241-04-6 O-phenyl N,N-dimethylthiocarbamate 
• 6304-33-2 2,3,3-triphenylacrylonitrile 

Relevant articles and documents

Regio- And diastereoselective synthesis of: Trans -3,4-diaryldihydrocoumarins via metal-free [4+2] annulation of ynamides with o -hydroxybenzyl alcohols

An efficient regio- and diastereoselective method for the construction of valuable trans-3,4-diaryldihydrocoumarins via metal-free [4+2] annulation of ynamides with o-hydroxybenzyl alcohols has been developed. Ynamides are first treated as 2-π partners to react with o-hydroxybenzyl alcohols via traceless sulfonamide directing groups, affording trans-3,4-diaryldihydrocoumarins in good yields with high regio- and diastereoselectivities. This metal-free methodology is also characterized by a wide substrate scope, good functional group tolerance, and efficiency on a gram scale.

The light “on-off” stepwise one-pot method for 3,4-diaryl coumarins with potential AIE properties

An efficient one-pot method involving visible-light-induced cyclization and Pd-catalyzed Suzuki cross-coupling processes to construct 3,4-diaryl coumarins is developed. Under the light on-off optimized conditions, a series of alkynoates and aryl boronic a

Visible-light-driven copper-catalyzed aerobic oxidative cascade cyclization of N-tosylhydrazones and terminal alkynes: Regioselective synthesis of 3-arylcoumarins

We present the first example of sustainable, intuitive, highly regioselective, visible-light-driven copper catalyzed aerobic oxidative cascade cyclization of N-tosylhydrazones with terminal alkynes for the preparation of 3-arylcoumarins at room temperature. This operationally simple methodology has been successfully applied to a wide range of N-tosylhydrazones and alkynes (49 examples), and proceeds well to afford biologically active compounds, such as monoamine oxidase B (MAO-B) inhibitor and horseradish peroxidase (HRP) inhibitor, in satisfactory yields under mild conditions. Furthermore, mechanistic studies suggest that the reaction proceeds via a copper(ii)-superoxo or -peroxo complex mediated oxidative annulation of terminal alkynes, as evidenced by 18O2 isotopic-labelling experiments.