71650-87-8

Basic information

• Product Name: 1,5-diphenylpentan-2-one
• Synonyms: 1,5-diphenylpentan-2-one
• CAS NO: 71650-87-8
• Molecular Weight: 238.329
• Mol File: 71650-87-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,5-diphenylpentan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-diphenylpentan-2-one(71650-87-8)
• EPA Substance Registry System: 1,5-diphenylpentan-2-one(71650-87-8)

Safety Data

• Hazardous Substances Data: 71650-87-8(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 1821-12-1 4-Phenylbutyric acid 
• 66310-10-9 N-benzyl-2,4,6-triphenylpyridinium tetrafluoroborate 
• 18496-54-3 phenylbutyric acid chloride 
• 1462-75-5 3-phenylpropylmagnesium bromide 
• 95092-10-7 N-methoxy-N-methyl-2-phenylacetamide 
• 1823-14-9 5-phenyl-1-pentyne 
• 71-43-2 benzene 
• 103-80-0 phenylacetyl chloride 
• 67556-37-0 (4-Methylsulfanyl-pent-4-enyl)-benzene 
• 100-56-1 phenylmercury(II) chloride 
• 108-86-1 bromobenzene 

Downstream Products

• 1718-50-9 1,5-diphenylpentane 

Relevant articles and documents

Nickel-Catalyzed Cross-Coupling of Alkyl Carboxylic Acid Derivatives with Pyridinium Salts via C-N Bond Cleavage

The electrophile-electrophile cross-coupling of carboxylic acid derivatives and alkylpyridinium salts via C-N bond cleavage is developed. The method is distinguished by its simplicity and steers us through a variety of functionalized ketones in good to excellent yields. Besides acid chlorides, carboxylic acids were also employed as acylating agents, which enabled us to incorporate acid-sensitive functional groups such as MOM, BOC, and acetal. Control experiments with TEMPO revealed a radical pathway.

Regioselective Arene and Heteroarene Functionalization: N-Alkenoxypyridinium Salts as Electrophilic Alkylating Agents for the Synthesis of α-Aryl/α-Heteroaryl Ketones

A direct regioselective functionalization of arenes and heteroarenes using N-alkenoxypyridinium salts as electrophilic alkylating agents for the synthesis of α-aryl/heteroaryl ketones has been developed. The method generates alkylating agents from alkynes and N-pyridine oxide followed by site-selective electrophilic substitution with a broad range of arenes and heteroarenes including benzene derivates, phenols, ethers, indoles, pyrroles, furans, and thiophenes in one pot. Kinetic isotope effect measurements and DFT studies reveal that this reaction likely proceeds through a carbon-cation intermediate.