717121-63-6

Basic information

• Product Name: 1-phenyl-1-(thiazol-2-yl)but-3-en-1-ol
• Synonyms: 1-phenyl-1-(thiazol-2-yl)but-3-en-1-ol
• CAS NO: 717121-63-6
• Molecular Weight: 231.318
• Mol File: 717121-63-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-phenyl-1-(thiazol-2-yl)but-3-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-1-(thiazol-2-yl)but-3-en-1-ol(717121-63-6)
• EPA Substance Registry System: 1-phenyl-1-(thiazol-2-yl)but-3-en-1-ol(717121-63-6)

Safety Data

• Hazardous Substances Data: 717121-63-6(Hazardous Substances Data)

Upstream product

• 433924-26-6 2-[allyloxy(phenyl)methyl]thiazole 
• 100-52-7 benzaldehyde 
• 879-52-7 phenyl-thiazol-2-yl-methanol 

Relevant articles and documents

Stereoselective and competitive [1,2]- and [2,3]-wittig rearrangements of allyl heteroarylalkyl ethers

Several allyl heteroarylalkyl ethers have been synthesized and then deprotonated with nBuLi in THF at -78°C to give lithium derivatives. The lithium-bearing terminus was either the α- or the α′-carbon atom, depending on the associated proton acidity. In the absence of an external electrophile, a sigmatropic rearrangement occurs, generating a new C-C bond. Heteroarylalkyl homoallylic alcohols and allyl heteroarylalkylic alcohols were obtained as products of stereoselective [2,3]- or [1,2]-Wittig rearrangements, respectively. Homoallylic alcohols were obtained in high yields and with fairly good enantiomeric enrichments when the reactions were carried out in toluene with (-)-sparteine as the external chiral ligand.