717134-47-9

Basic information

• Product Name: METHYL 6-CHLORO-1H-INDAZOLE-3-CARBOXYLATE
• Synonyms: METHYL 6-CHLORO-1H-INDAZOLE-3-CARBOXYLATE;6-Chloro-1H-indazole-3-carboxylic acid Methyl ester
• CAS NO: 717134-47-9
• Molecular Formula: C9H7ClN2O2
• Molecular Weight: 210.62
• Mol File: 717134-47-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 378.7±22.0 °C(Predicted)
• Appearance: /
• Density: 1.453±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 10.75±0.40(Predicted)
• CAS DataBase Reference: METHYL 6-CHLORO-1H-INDAZOLE-3-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 6-CHLORO-1H-INDAZOLE-3-CARBOXYLATE(717134-47-9)
• EPA Substance Registry System: METHYL 6-CHLORO-1H-INDAZOLE-3-CARBOXYLATE(717134-47-9)

Safety Data

• Hazardous Substances Data: 717134-47-9(Hazardous Substances Data)

Usage

General Description

Methyl 6-chloro-1H-indazole-3-carboxylate is a chemical compound with the molecular formula C9H7ClN2O2. It is a derivative of indazole, which is a heterocyclic compound commonly used in pharmaceuticals and agrochemicals. This particular compound is a methyl ester of 6-chloro-1H-indazole-3-carboxylic acid, and it has potential applications in the development of new drugs or as an intermediate in organic synthesis. Its molecular structure makes it a versatile building block for the creation of various complex organic compounds, and it may have biological activity that could be beneficial in pharmaceutical development.

Upstream product

• 717134-46-8 (2-acetylamino-4-chloro-phenyl)-acetic acid methyl ester 
• 67-56-1 methanol 
• 503045-59-8 6-chloro-3-iodo-1H-indazole 
• 201230-82-2 carbon monoxide 
• 698-25-9 6-chloro-1H-indazole 
• 553-90-2 Dimethyl oxalate 
• 695-56-7 1,4-dioxaspiro[4.4]non-6-ene 

Relevant articles and documents

De Novo Synthesis of Benzannelated Heterocycles

Benzannelated heterocycles such as indoles and indazoles are prominent structural motifs found in natural products, pharmaceuticals and agrochemicals. For their synthesis, chemists traditionally either functionalize commercially available heterocycles or resort to transformations that make use of benzene-derived building blocks. Here, we report a powerful cascade reaction that enables the de novo construction of variously substituted indoles, indazoles, benzofurans and benzothiophenes from readily available bicyclo[3.1.0]hexan-2-ones. The transformation can be conducted under mild, non-anhydrous conditions. For the synthesis of indoles, mechanistic studies revealed that the electrocyclic ring-opening of the bicyclic ring-system and aromatization precedes the 3,3-sigmatropic rearrangement.

CONDENSED PYRAZOLE DERIVATIVES AS PPAR AGONISTS II

The invention discloses compounds of formula (I) wherein: R is a carboxylic acid or a derivative thereof; R1 and R2 are independently H or alkyl, or together R1 and R2 form an alkylene group; L1 is a