71721-13-6Relevant articles and documents
Directed Lithiation of Chlorobenzenes. Regioselectivity and Application to a Short Synthesis of Benzocyclobutenes
Iwao, Masatomo
, p. 3622 - 3627 (2007/10/02)
Chlorobenzene and its OMe, OSiMe2-t-Bu, and Cl derivatives 1 were lithiated with high regioselectivity ortho to chlorine by treatment with sec-BuLi in THF at -105 deg C without complications due to benzyne formation.The lithio species thus generated under