71759-87-0 Usage
Description
4-Iodo-1-methyl-1H-imidazole is an organic compound with the molecular formula C4H5IN2. It is a heterocyclic compound featuring an imidazole ring, which is a five-membered ring containing two nitrogen atoms and one methyl group attached to the 1-position. The 4-position of the imidazole ring is substituted with an iodine atom, which makes it a valuable intermediate in the synthesis of various chemical compounds.
Uses
Used in Pharmaceutical Industry:
4-Iodo-1-methyl-1H-imidazole is used as a chemical reagent for the synthesis of positron emission tomography (PET) tracers. These tracers are essential in medical imaging, particularly for visualizing and studying the function of brain enzymes. The iodine atom in the compound allows for the detection of these tracers through PET imaging, providing valuable insights into the diagnosis and treatment of neurological disorders.
Used in Research and Development:
In addition to its application in the pharmaceutical industry, 4-Iodo-1-methyl-1H-imidazole is also utilized in research and development for the synthesis of novel compounds with potential applications in various fields, such as materials science, chemistry, and biology. Its unique structure and reactivity make it a versatile building block for the development of new molecules with specific properties and functions.
Check Digit Verification of cas no
The CAS Registry Mumber 71759-87-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,7,5 and 9 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 71759-87:
(7*7)+(6*1)+(5*7)+(4*5)+(3*9)+(2*8)+(1*7)=160
160 % 10 = 0
So 71759-87-0 is a valid CAS Registry Number.
InChI:InChI=1/C4H5IN2.ClH/c1-7-2-4(5)6-3-7;/h2-3H,1H3;1H
71759-87-0Relevant articles and documents
Expedient total syntheses of preclathridine A and clathridine A
Koswatta, Panduka B.,Lovely, Carl J.
, p. 4998 - 5000 (2009)
A short and operationally simple total synthesis of two Leucetta-derived marine alkaloids has been developed, which rely on position specific halogen-metal exchange to introduce the benzyl-substituted side chain. Introduction of the C2 amine group by lith
MYST FAMILY HISTONE ACETYLTRANSFERASE INHIBITORS
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Paragraph 0293-0295; 0292, (2019/06/19)
The present disclosure provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
Total synthesis and cytotoxicity of Leucetta alkaloids
Koswatta, Panduka B.,Kasiri, Sabha,Das, Jayanta K.,Bhan, Arunoday,Lima, Heather M.,Garcia-Barboza, Beatriz,Khatibi, Nicole N.,Yousufuddin, Muhammed,Mandal, Subhrangsu S.,Lovely, Carl J.
, p. 1608 - 1621 (2017/02/26)
The total synthesis of a number of representative natural products isolated from Leucetta and Clathrina sponges containing a polysubstituted 2-aminoimidazole are described. These syntheses take advantage of the site specific metallation reactions of 4,5-diiodoimidazoles resulting in the syntheses of three different classes of Leucetta derived natural products. The cytotoxicities of these natural products, along with several precursors in MCF7 cells were determined through an MTT growth assay. For comparative purposes a series of naphthimidazole-containing family members are included.
