718-27-4

Basic information

• Product Name: 2-[2-(p-Tolyl)ethenyl]pyridine
• Synonyms: 2-(4-Methylstyryl)pyridine;2-[2-(p-Tolyl)ethenyl]pyridine
• CAS NO: 718-27-4
• Molecular Formula: C14H13N
• Molecular Weight: 195.26
• Mol File: 718-27-4.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 318.8°C at 760 mmHg
• Flash Point: 135.6°C
• Appearance: /
• Density: 1.072g/cm³
• Vapor Pressure: 0.000658mmHg at 25°C
• Refractive Index: 1.651
• CAS DataBase Reference: 2-[2-(p-Tolyl)ethenyl]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(p-Tolyl)ethenyl]pyridine(718-27-4)
• EPA Substance Registry System: 2-[2-(p-Tolyl)ethenyl]pyridine(718-27-4)

Safety Data

• Hazardous Substances Data: 718-27-4(Hazardous Substances Data)

Usage

General Description

2-[2-(p-Tolyl)ethenyl]pyridine, also known as p-Tolylstilbene, is a chemical compound with the molecular formula C18H15N. It is a derivative of stilbene and contains a pyridine ring. 2-[2-(p-Tolyl)ethenyl]pyridine is utilized in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. It exhibits both fluorescent and phosphorescent properties which make it suitable for use in the manufacturing of light-emitting diodes (LEDs) and organic solar cells. Additionally, it has been investigated for its potential anti-inflammatory and anti-cancer properties, making it a subject of interest in the field of medicinal chemistry.

InChI:InChI=1/C14H13N/c1-12-5-7-13(8-6-12)9-10-14-4-2-3-11-15-14/h2-11H,1H3

Upstream product

• 100-69-6 2-vinylpyridine 
• 2028-84-4 p-methylbenzenediazonium chloride 
• 109-06-8 α-picoline 
• 104-87-0 4-methyl-benzaldehyde 
• 500-22-1 3-pyridinecarboxaldehyde 
• 3762-25-2 diethyl 4-methylbenzylphosphonate 
• 110-86-1 pyridine 
• 4186-14-5 1-(2-(trimethylsilyl)ethynyl)toluene 
• 159493-94-4 1-(2-pyridylmethyl)-1H-benzotriazole 
• 106-38-7 para-bromotoluene 
• 5720-05-8 4-methylphenylboronic acid 
• 38700-15-1 triphenyl-(2-pyridylmethyl)phosphonium chloride 
• 5825-13-8 (Z)-2-(p-tolylstyryl)pyridine 
• 121-69-7 N,N-dimethyl-aniline 

Relevant articles and documents

Carbanionic displacement reactions at phosphorus: Diethyl (2-pyridyl)methylphosphonate synthesis

We describe the formation and reactions of the α-lithiated (2-pyridyl)methylphosphonate 1. The lithiated α-picoline is obtained by metallation in THF at low temperature with LDA (lithium diisopropylamide) (2 equiv.). This is then condensed with diethyl ch

A new Pd(II)-supported catalyst on magnetic SBA-15 for C-C bond formation via the Heck and Hiyama cross-coupling reactions

Magnetic mesoporous silica composite (MNP@SiO2-SBA) was obtained via embedding magnetite nanoparticles between SBA-15 channels. It was silylated with N-(3-(trimethoxysilyl)propyl)picolinamide (TMS-PCA) and then complexed with Pd(II). The obtained supported Pd(II) catalyst (MNP@SiO2-SBA-PCA) was characterized by conventional methods. The prepared magnetic catalyst showed high activity in the Heck and Hiyama reactions under optimal reaction conditions, including solvent, amount of catalyst, base, and temperature. Aryl bromides and iodides showed better results than aryl chlorides, and the catalyst exhibited noticeable stability and reused several times.

Determination and application of the excited-state substituent constants of pyridyl and substituted phenyl groups

Thirty six 1-pyridyl-2-arylethenes XCH=CHArY (abbreviated XAEY) were synthesized, in which, X is 2-pyridyl, 3-pyridyl and 4-pyridyl and Y is OMe, Me, H, Br, Cl, F, CF3, and CN. Their ultraviolet absorption spectra were measured in anhydrous ethanol, and their wavelengths of absorption maximum λmax were recorded. Also, the 234 λmax values of 1-substituted phenyl-2-arylethylene compounds (XAEY, where X is substituted phenyl) were collected. The excited-state substituent constants (Formula presented.) of three pyridyl groups and 23 substituted phenyl groups (total of 26) were obtained by means of curve-fitting method. Taking the λmax values of 358 samples of bi-arylethene derivatives as a data set and 126 samples of bi-aryl Schiff bases (including nine compounds synthesized by this work) as another data set, quantitative correlation analyses were performed by employing the obtained (Formula presented.) as a parameter, and good results were obtained for the two data sets. The reliability of the obtained (Formula presented.) values was verified. The results of this paper can provide excited-state substituent constants for the study and application of optical properties of conjugated organic compounds containing aryl groups.