719-79-9

Basic information

• Product Name: 1,4-DIPHENYLBUTANE
• Synonyms: (1-Phenylbutyl)benzene;1,1’-butylidenebis-benzen;Benzene, 1,1'-butylidenebis-;benzene,1,1’-butylidenebis-;butane,1,1-diphenyl-;1,4-DIPHENYLBUTANE;1,4-DIPHENYL-N-BUTANE;1,1-DIPHENYLBUTANE
• CAS NO: 719-79-9
• Molecular Formula: C₁₆H₁₈
• Molecular Weight: 210.31
• Mol File: 719-79-9.mol
• Article Data: 15

Chemical Properties

• Melting Point: -25.2°C
• Boiling Point: 287.05°C
• Flash Point: 136.8°C
• Appearance: /
• Density: 0.9712 (estimate)
• Vapor Pressure: 0.0044mmHg at 25°C
• Refractive Index: 1.5546
• CAS DataBase Reference: 1,4-DIPHENYLBUTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-DIPHENYLBUTANE(719-79-9)
• EPA Substance Registry System: 1,4-DIPHENYLBUTANE(719-79-9)

Safety Data

• Hazardous Substances Data: 719-79-9(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Synthetic Communications, 10, p. 939, 1980 DOI: 10.1080/00397918008061855

InChI:InChI=1/C16H18/c1-2-9-16(14-10-5-3-6-11-14)15-12-7-4-8-13-15/h3-8,10-13,16H,2,9H2,1H3

Upstream product

• 64-17-5 ethanol 
• 141-52-6 sodium ethanolate 
• 541-33-3 1,1-dichlorobutane 
• 1726-14-3 1,1-diphenyl-1-butene 
• 7495-83-2 n-butyl diphenylmethyl ether 
• 10557-57-0 propylmagnesium iodide 
• 5331-17-9 1,1-diphenylbutan-1-ol 
• 29949-16-4 2,2’-diphenylpentanenitrile 
• 861777-12-0 2-benzhydryl-1-phenyl-butan-1-one 
• 123-72-8 butyraldehyde 
• 71-43-2 benzene 
• 616-21-7 1,2-dichlorobutane 
• 75-77-4 chloro-trimethyl-silane 
• 85316-36-5 4,4-diphenylbutyllithium 

Downstream Products

• 54890-00-5 1,1-dicyclohexyl-butane 
• 854458-55-2 1,1-bis-(4-nitro-phenyl)-butane 
• 3370-19-2 4,4-Diphenyl-8-diethylamino-octin-⁽⁶⁾ 
• 6431-56-7 4,4,9,9-Tetraphenyl-dodecan 
• 6393-07-3 1,2,2-Triphenyl-pentan 
• 6393-06-2 1,3,3-Triphenyl-hexan 
• 69318-56-5 1,1-bis-(4-amino-phenyl)-butane 

Relevant articles and documents

Ligand-Enabled Nickel-Catalyzed Redox-Relay Migratory Hydroarylation of Alkenes with Arylborons

A redox-relay migratory hydroarylation of isomeric mixtures of olefins with arylboronic acids catalyzed by nickel complexes bearing diamine ligands is described. A range of structurally diverse 1,1-diarylalkanes, including those containing a 1,1-diarylated quaternary carbon, were obtained in excellent yields and with high regioselectivity. Preliminary experimental evidence supports the proposed non-dissociated chainwalking of aryl-nickel(II)-hydride species along the alkyl chain of alkenes before selective reductive elimination at a benzylic position. A catalyst loading as low as 0.5 mol % proved to be sufficient in large-scale synthesis while retaining high reactivity, highlighting the practical value of this transformation.

Ligand-Controlled Nickel-Catalyzed Reductive Relay Cross-Coupling of Alkyl Bromides and Aryl Bromides

1,1-Diarylalkanes are important structural frameworks which are widespread in biologically active molecules. Herein, we report a reductive relay cross-coupling of alkyl bromides with aryl bromides by nickel catalysis with a simple nitrogen-containing ligand. This method selectively affords 1,1-diarylalkane derivatives with good to excellent yields and regioselectivity.

Zinc chloride enhanced arylations of secondary benzyl trifluoroacetates in the presence of b-hydrogen atoms

Zinc or swim: Arylation of benzyl trifluoroacetates with arylzinc reagents in the presence of β- hydrogen atoms were realized under mild conditions. Both electron-rich and electron-deficient arene substrates were successfully arylated. This arylation method could offer a very versatile synthetic route to access a series of diversity-oriented diarylalkane motifs. TFA = trifluoroacetyl. Copyright