71907-26-1

Basic information

• Product Name: Benzoxazole, 2-[2-(4-chlorophenyl)ethenyl]-, (E)-
• CAS NO: 71907-26-1
• Molecular Formula: C15H10ClNO
• Molecular Weight: 255.703
• Mol File: 71907-26-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzoxazole, 2-[2-(4-chlorophenyl)ethenyl]-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoxazole, 2-[2-(4-chlorophenyl)ethenyl]-, (E)-(71907-26-1)
• EPA Substance Registry System: Benzoxazole, 2-[2-(4-chlorophenyl)ethenyl]-, (E)-(71907-26-1)

Safety Data

• Hazardous Substances Data: 71907-26-1(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 273-53-0 benzoxazole 
• 1073-67-2 4-vinylbenzyl chloride 
• 1615-02-7 3-(4-chlorophenyl)prop-2-enoic acid 
• 95-55-6 2-amino-phenol 
• 29805-11-6 1-(4-chlorophenyl)prop-2-yn-1-ol 
• 41014-43-1 2-(chloromethyl)benzoxazole 
• 95-21-6 2-methyl-1,3-benzoxazole 

Relevant articles and documents

Copper-Catalyzed Regio- and Enantioselective Addition of Silicon Grignard Reagents to Alkenes Activated by Azaaryl Groups

A new application of silicon Grignard reagents in C(sp3)?Si bond formation is reported. With the aid of BF3?OEt2, these silicon nucleophiles add across alkenes activated by various azaaryl groups under copper catalysis. An enantioselective version employing benzoxazole-activated alkenes as substrates and a CuI-josiphos complex as catalyst has been developed, forming the C(sp3)?Si bond with good to high enantiomeric ratios (up to 97:3). The method expands the toolbox for “conjugate addition” type C(sp3)?Si bond formation.

Trichloroisocyanuric Acid/Triphenylphosphine-Mediated Synthesis of Benzimidazoles, Benzoxazoles, and Benzothiazoles

A new and efficient method for preparation of benzimidazoles, benzoxazoles, and benzothiazoles from reactions of different carboxylic acids with o-phenylenediamine, o-aminophenol, and o-aminothiophenol in the presence of triphenylphosphine/trichloroisocyanuric acid system is presented. The desired products have been characterised on the basis of spectral (infrared, NMR, mass spectrometry) data, and the mechanism of their formation is proposed. The remarkable advantages are the inexpensive and readily available reagent, simple procedure, mild conditions, and good-to-excellent yields.

Ligand promoted Pd-catalyzed dehydrogenative alkenylation of hetereoarenes

An efficient Pd-catalyzed cross-dehydrogenative coupling of heteroarenes with styrenes and other olefinic substrates has been developed. This alkenylation paradigm encompasses a wide range of substrates and provides a straightforward approach toward C2-E-alkenylated azole motifs. This journal is the Partner Organisations 2014.