Welcome to LookChem.com Sign In|Join Free

CAS

  • or

72016-68-3

Post Buying Request

72016-68-3 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

72016-68-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 72016-68-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,0,1 and 6 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 72016-68:
(7*7)+(6*2)+(5*0)+(4*1)+(3*6)+(2*6)+(1*8)=103
103 % 10 = 3
So 72016-68-3 is a valid CAS Registry Number.

72016-68-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name ETHYL 2-(5-BROMO-2-METHYL-1H-INDOL-3-YL)ACETATE

1.2 Other means of identification

Product number -
Other names ethyl (5-bromo-2-methylindol-3-yl)acetate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:72016-68-3 SDS

72016-68-3Relevant articles and documents

Indole compounds with: N-ethyl morpholine moieties as CB2 receptor agonists for anti-inflammatory management of pain: Synthesis and biological evaluation

Ji, Jing,Li, Jiaojiao,Li, Zhengfu,Xu, Ruibo

supporting information, p. 1935 - 1947 (2019/11/20)

The CB2 receptor plays a crucial role in analgesia and anti-inflammation. To develop novel CB2 agonists with high efficacy and selectivity, a series of indole derivatives with N-ethyl morpholine moieties (compounds 1-56) were designed, synthesized and biologically evaluated. Compounds 1, 2, 3, 46 and 53 exhibited high CB2 receptor affinity at low nanomolar concentrations and good receptor selectivity (EC50(CB1)/EC50(CB2) greater than 1000). The most active compound, compound 2, was more potent than the standard drug GW405833 for in vitro agonistic action on the CB2 receptor. More importantly, in a rat model for CFA-induced inflammatory hyperalgesia, compound 2 had a potent anti-inflammatory pain effect within 12 hours after administration. At the 1 h time point, compound 2 had a dose-dependent reversal for hyperalgesia with an estimated ED50 value of 1.097 mg kg-1. Moreover, compound 2 significantly suppressed the pro-inflammatory cytokines (IL-1β, IL-6 and TNF-α) in CFA-induced lesions. These protective effects of compound 2 on inflammatory pain were superior to those of GW405833, suggesting that compound 2 may be a promising therapeutic drug that needs further validation.

Discovery and refinement of a new structural class of potent peptide deformylase inhibitors

Boularot, Adrien,Giglione, Carmela,Petit, Sylvain,Duroc, Yann,De Sousa, Rodolphe Alves,Larue, Valéry,Cresteil, Thierry,Dardel, Frédéric,Artaud, Isabelle,Meinnel, Thierry

, p. 10 - 20 (2007/10/03)

New classes of antibiotics are urgently needed to counter increasing levels of pathogen resistance. Peptide deformylase (PDF) was originally selected as a specific bacterial target, but a human homologue, the inhibition of which causes cell death, was rec

Hypoglycemic imidazoline compounds

-

Page/Page column 18, (2010/02/05)

This invention relates to certain novel imidazoline compounds and analogues thereof, to their use for the treatment of diabetes, diabetic complications, metabolic disorders, or related diseases where impaired glucose disposal is present, to pharmaceutical compositions comprising them, and to processes for their preparation.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 72016-68-3