720708-11-2

Basic information

• Product Name: 4-(3-Carboxy-phenyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester
• Synonyms: 4-(3-Carboxy-phenyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester
• CAS NO: 720708-11-2
• Molecular Weight: 287.315
• Mol File: 720708-11-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(3-Carboxy-phenyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-Carboxy-phenyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester(720708-11-2)
• EPA Substance Registry System: 4-(3-Carboxy-phenyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester(720708-11-2)

Safety Data

• Hazardous Substances Data: 720708-11-2(Hazardous Substances Data)

Upstream product

• 5408-07-1 ethyl 4-bromo-3,5-dimethylpyrrole-2-carboxylate 
• 25487-66-5 3-Carboxyphenylboronic acid 

Downstream Products

• 720708-09-8 4-[3-(4-isopropyl-phenylcarbamoyl)-phenyl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 720708-27-0 4-[3-(3-isopropyl-phenylcarbamoyl)-phenyl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 775322-46-8 3-(2,4-dimethyl-1H-pyrrol-3-yl)-benzoic acid 

Relevant articles and documents

5-sulfonamido-substituted indolinone compounds as protein kinase inhibitors

The present invention relates to 5-sulfonamido substituted indolinones that modulate the activity of protein kinases (“PKs”). The compounds of this invention are therefore useful in treating disorders related to abnormal PK activity. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.

Substituted pyrroles as kinase inhibitors

The present invention relates to certain substituted pyrroles which modulate the activity of protein kinases (“PKs”). The compounds of this invention are therefore useful in treating disorders related to abnormal PK activity. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.