7216-46-8Relevant articles and documents
Thiazole formation through a modified Gewald reaction
Mallia, Carl J.,Englert, Lukas,Walter, Gary C.,Baxendale, Ian R.
, p. 875 - 883 (2015/08/24)
The synthesis of thiazoles and thiophenes starting from nitriles, via a modified Gewald reaction has been studied for a number of different substrates. 1,4-Dithiane-2,5-diol was used as the aldehyde precursor to give either 2-substituted thiazoles or 2-substituted aminothiophenes depending on the substitution of the α-carbon to the cyano group.
A facile experimental method to determine the hydride affinity of polarized olefins in acetonitrile
Zhu, Xiao-Qing,Zhang, Min,Liu, Qiao-Yun,Wang, Xiao-Xiao,Zhang, Jian-Yu,Cheng, Jin-Pei
, p. 3954 - 3957 (2007/10/03)
(Chemical Equation Presented) Choosing a suitable hydride reducing agent and thermodynamic analysis of reduction mechanisms is facilitated by experimental hydride affinities ΔHH-A, which are reported herein for 28 polarized olefins 1 in acetonitrile (see scheme). The method should also be applicable to ketones, aldehydes, and imines.
Synthesis of some disubstituted cyanoacetamides as potential anticonvulsants.
Schwartz 2nd.,Worrell,Delgado
, p. 80 - 86 (2007/10/10)
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