72170-88-8Relevant articles and documents
An efficient protocol for the oxidative hydrolysis of ketone SAMP hydrazones employing SeO2 and H2O2 under buffered (pH 7) conditions
Smith III, Amos B.,Liu, Zhuqing,Simov, Vladimir
experimental part, p. 3131 - 3134 (2010/03/24)
An effective oxidative protocol for the liberation of ketones from SAMP hydrazones employing peroxyselenous acid under aqueous buffered conditions (pH 7) has been developed. The procedure proceeds without epimerization of adjacent stereocenters or dehydration, in representative SAMP alkylation and aldol reaction adducts, respectively.
Asymmetric Synthesis of α′-Silylated α-Iodo Ketones via Iodination with Trifluoroiodomethane
Enders, Dieter,Klein, Daniela,Raabe, Gerhard,Runsink, Jan
, p. 1271 - 1272 (2007/10/03)
The diastereo- and enantioselective syntheses of various α′-t-butyldimethylsilyl-α-iodo ketones 4a-h is described. The carbon iodine bond formation is achieved using trifluoroiodomethane as the electrophilic iodination reagent. The iodo ketones 4 are obtained in good yields and with excellent diastereo- and enantiomeric excesses (de,ee ≥ 98%).
