72178-38-2

Basic information

• Product Name: N-(4-ACETYL-PHENYL)-4-CHLORO-BENZENESULFONAMIDE
• Synonyms: benzenesulfonamide, N-(4-acetylphenyl)-4-chloro-; N-(4-Acetyl-phenyl)-4-chloro-benzenesulfonamide
• CAS NO: 72178-38-2
• Molecular Formula: C₁₄H₁₂ClNO₃S
• Molecular Weight: 309.768
• Mol File: 72178-38-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 475.7 °C at 760 mmHg
• Flash Point: 241.5 °C
• Appearance: /
• Density: 1.395 g/cm³
• Vapor Pressure: 3.25E-09mmHg at 25°C
• Refractive Index: 1.621
• CAS DataBase Reference: N-(4-ACETYL-PHENYL)-4-CHLORO-BENZENESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-ACETYL-PHENYL)-4-CHLORO-BENZENESULFONAMIDE(72178-38-2)
• EPA Substance Registry System: N-(4-ACETYL-PHENYL)-4-CHLORO-BENZENESULFONAMIDE(72178-38-2)

Safety Data

• Hazardous Substances Data: 72178-38-2(Hazardous Substances Data)

Usage

General Description

N-(4-ACETYL-PHENYL)-4-CHLORO-BENZENESULFONAMIDE, also known as AC1019, is a chemical compound with potential applications in the field of drug development and medicinal chemistry. It belongs to the class of sulphonamide compounds and contains a benzene ring with a chloro substitution and an acetylphenyl group. N-(4-ACETYL-PHENYL)-4-CHLORO-BENZENESULFONAMIDE has shown potential as an anti-inflammatory and analgesic agent, with studies suggesting its ability to inhibit the production of inflammatory mediators. Additionally, it has been investigated for its potential use in the treatment of cancer due to its ability to inhibit the growth of cancer cells. Further research is needed to fully understand the pharmacological properties and potential therapeutic uses of N-(4-ACETYL-PHENYL)-4-CHLORO-BENZENESULFONAMIDE.

InChI:InChI=1/C14H12ClNO3S/c1-10(17)11-2-6-13(7-3-11)16-20(18,19)14-8-4-12(15)5-9-14/h2-9,16H,1H3

Upstream product

• 99-92-3 p-aminobenzophenone 
• 98-60-2 4-chlorobenzenesulfonyl chloride 

Downstream Products

• 72178-57-5 4-Chloro-N-[4-((E)-3-furan-2-yl-acryloyl)-phenyl]-benzenesulfonamide 
• 72178-54-2 4-Chloro-N-{4-[(E)-3-(4-chloro-phenyl)-acryloyl]-phenyl}-benzenesulfonamide 
• 174367-24-9 4-Chloro-N-{4-[(E)-3-(2-chloro-phenyl)-acryloyl]-phenyl}-benzenesulfonamide 
• 72187-95-2 4-Chloro-N-{4-[(E)-3-(3-nitro-phenyl)-acryloyl]-phenyl}-benzenesulfonamide 
• 72178-49-5 4-Chloro-N-{4-[(E)-(3-phenyl-acryloyl)]-phenyl}-benzenesulfonamide 
• 174367-26-1 4-Chloro-N-{4-[(E)-3-(4-methoxy-phenyl)-acryloyl]-phenyl}-benzenesulfonamide 
• 174367-27-2 4-Chloro-N-{4-[(E)-3-(3,4-dimethoxy-phenyl)-acryloyl]-phenyl}-benzenesulfonamide 
• 174367-25-0 4-Chloro-N-{4-[(E)-3-(2-methoxy-phenyl)-acryloyl]-phenyl}-benzenesulfonamide 
• 562086-45-7 4-Chloro-N-{4-[(E)-3-(4-dimethylamino-phenyl)-acryloyl]-phenyl}-benzenesulfonamide 

Relevant articles and documents

Design and synthesis of some novel 4-Chloro-N-(4-(1-(2-(2-cyanoacetyl)hydrazono)ethyl)phenyl) benzenesulfonamide derivatives as anticancer and radiosensitizing agents

A novel series of sulfonamide derivatives 4e21 have been synthesized starting from the strategic starting material (E)-4-Chloro-N-(4-(1-(2-(2-cyanoacetyl)hydrazono)ethyl)phenyl) benzenesulfonamide 4. Two series of hydrazone 5e9, and pyridone 10e21 derivat

Purine-ring-containing benzene sulfonamide chalcone derivative and preparation and application methods thereof

The invention discloses a purine-ring-containing benzene sulfonamide chalcone derivative and preparation and application methods thereof. The purine-ring-containing benzene sulfonamide chalcone derivative has a formula (I) shown as below, in which R1 is 4-oxymethyl, 4-tert-butyl, 4-methyl, 4-flouride, 4-bromide, 2-methyl, 2-fluoride, 2-chloride, 2-bromide and hydrogen atom and R2 is methyl, ethyland benzyl. The purine-ring-containing benzene sulfonamide chalcone derivative can inhibit tobacco mosaic virus, cucumber mosaic virus, potato Y virus and southern rice black-streaked dwarf virus.