72189-44-7 Usage
Description
C9H10O5, also known as Salbutamol Glyoxal Impurity, is a chemical compound synthesized from 3-Chloromethyl-4-hydroxyacetophenone (C369215). It is an impurity found in the production of Salbutamol, a medication used for treating asthma and other respiratory conditions.
Uses
Used in Pharmaceutical Industry:
C9H10O5 is used as a reference standard for quality control and analytical testing in the pharmaceutical industry. It helps ensure the purity and safety of Salbutamol products by providing a benchmark for comparison during the manufacturing process.
Used in Research and Development:
C9H10O5 serves as a valuable compound for researchers studying the synthesis, properties, and potential applications of Salbutamol and its related compounds. It can be used to investigate the mechanisms of action, side effects, and interactions with other drugs in the development of new treatments for respiratory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 72189-44-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,1,8 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 72189-44:
(7*7)+(6*2)+(5*1)+(4*8)+(3*9)+(2*4)+(1*4)=137
137 % 10 = 7
So 72189-44-7 is a valid CAS Registry Number.
72189-44-7Relevant articles and documents
Method for preparing Vilanterol
-
, (2019/04/17)
The invention discloses a method for preparing Vilanterol, and belongs to the field of drug synthesis. The method includes the steps: (1) performing addition reaction on salicyloyl and glyoxylic acidto generate an intermediate 1; (2) performing chiral resolution on the intermediate 1 to obtain a chiral intermediate 2; (3) performing acylation reaction on the intermediate 2 and an intermediate 3 to generate an intermediate 4; (4) reducing the intermediate 4 to obtain the Vilanterol. The intermediate 3 is obtained by performing Darebin reaction on an intermediate 5. Raw materials are easily obtained, a synthetic route is short, production cost is reduced, reaction conditions are mild, and the method is simple in operation and suitable for industrial production.
Preparation method of vilanterol intermediate
-
Paragraph 0022; 0025; 0026; 0027; 0028, (2019/05/08)
The invention discloses a preparation method of a vilanterol intermediate and belongs to the field of drug synthesis. The method is characterized in that 4-hydroxy-mandelic acid is taken as a raw material and is subjected to formylation reaction to obtain
