72229-57-3

Basic information

• Product Name: 2-methyl-2-(2-acetoxy-5-methoxyphenyl)cyclopentane-1,3-dione
• Synonyms: 2-methyl-2-(2-acetoxy-5-methoxyphenyl)cyclopentane-1,3-dione
• CAS NO: 72229-57-3
• Molecular Weight: 276.289
• Mol File: 72229-57-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methyl-2-(2-acetoxy-5-methoxyphenyl)cyclopentane-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-2-(2-acetoxy-5-methoxyphenyl)cyclopentane-1,3-dione(72229-57-3)
• EPA Substance Registry System: 2-methyl-2-(2-acetoxy-5-methoxyphenyl)cyclopentane-1,3-dione(72229-57-3)

Safety Data

• Hazardous Substances Data: 72229-57-3(Hazardous Substances Data)

Upstream product

• 17082-61-0 1,2-bis(trimethylsiloxy)cyclobutene 
• 72229-47-1 2'-acetoxy-5'-methoxyacetophenone 

Downstream Products

• 72229-64-2 5-bromo-2-methyl-3α-acetoxy-2-(2-acetoxy-5-methoxyphenyl)cyclopentanone 
• 72229-63-1 2-methyl-3α-acetoxy-2-(2-acetoxy-5-methoxyphenyl)cyclopentanone 

Relevant articles and documents

Synthesis of C-Ring-Functionalized A-Ring-Aromatic Trichothecane Analogues

15,16-Dinor-4α-acetoxy-8-methoxy-6,8,10-trichothecatriene 12,13-epoxide (11) was prepared from 2α-(2-acetoxy-5-methoxyphenyl)-2β-methyl-3α-acetoxycyclopentanone (8) in three steps (bromination, DBN-induced cyclization, and spiroepoxidation).The cyclopentanone 8 was prepared from the hemiketal 6a which was prepared from 2'-acetoxy-5'-methoxyacetophenone (3f) in a reaction sequence involving the boron trifluoride catalyzed aldol addition of 1,2-bis(trimethylsilyloxy)cyclobutene followed by a trifluoroacetic acid catalyzed pinacol rearrangement of the cyclobutanone intermediate.