72278-09-2

Basic information

• Product Name: Ethanone, 1-(3-nitrophenyl)-, O-methyloxime
• Synonyms: 2.4-Dinitrophenylhydrazon des m-Nitro-acetophenons;-2.4-dinitrophenylhydrazon;m-Nitroacetophenone oxime methyl ether;3-Nitro-acetophenon-<2.4-dinitro-phenylhydrazon>;3'-nitroacetophenone 2,4-dinitrophenylhydrazone;
• CAS NO: 72278-09-2
• Molecular Formula: C9H10N2O3
• Molecular Weight: 194.19
• Mol File: 72278-09-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(3-nitrophenyl)-, O-methyloxime(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(3-nitrophenyl)-, O-methyloxime(72278-09-2)
• EPA Substance Registry System: Ethanone, 1-(3-nitrophenyl)-, O-methyloxime(72278-09-2)

Safety Data

• Hazardous Substances Data: 72278-09-2(Hazardous Substances Data)

Upstream product

• 15754-20-8 (E)-acetophenone O-methyloxime 
• 121-89-1 3-Nitroacetophenone 
• 7471-32-1 m-nitroacetophenone oxime 
• 74-88-4 methyl iodide 

Downstream Products

• 40788-04-3 1-(1,1-difluoroethyl)-3-nitro-benzene 
• 1439930-80-9 (E)-1-(2,5-dinitrophenyl)ethanone O-methyl oxime 
• 121-89-1 3-Nitroacetophenone 
• 90271-37-7 3-nitro-α-methylbenzylamine 

Relevant articles and documents

Monomeric Octahedral Ruthenium(II) Complex Enabled meta-C-H Nitration of Arenes with Removable Auxiliaries

A removable oxime-assisted meta-C-H nitration of arenes is reported. Mechanistic investigations and DFT calculations reveal a new monomeric octahedral ruthenium(II) complex is responsible for the meta-selective nitration. Dioxygen as a cooxidant is crucial for achieving high conversion and good yields. Moreover, the utility of the present reaction protocol is further showcased by the late-stage modification of the clinical CNS drugs Diazepam and Fluvoxamine.