724-43-6

Basic information

• Product Name: ethyl 1-acetyl-1H-indazole-6-carboxylate
• Synonyms: ethyl 1-acetyl-1H-indazole-6-carboxylate
• CAS NO: 724-43-6
• Molecular Weight: 232.239
• Mol File: 724-43-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 1-acetyl-1H-indazole-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-acetyl-1H-indazole-6-carboxylate(724-43-6)
• EPA Substance Registry System: ethyl 1-acetyl-1H-indazole-6-carboxylate(724-43-6)

Safety Data

• Hazardous Substances Data: 724-43-6(Hazardous Substances Data)

Upstream product

• 41191-92-8 3-amino-4-methylbenzoic acid ethyl ester 
• 127-08-2 potassium acetate 
• 108-24-7 acetic anhydride 

Downstream Products

• 916902-55-1 6-(hydroxymethyl)-1H-indazole 

Relevant articles and documents

Divergent Synthesis of Molecular Winch Prototypes

We report the synthesis of conceptually new prototypes of molecular winches with the ultimate aim to investigate the work performed by a single ruthenium-based molecular motor anchored on a surface by probing its ability to pull a load upon electrically-driven directional rotation. According to a technomimetic design, the motor was embedded in a winch structure, with a long flexible polyethylene glycol chain terminated by an azide hook to connect a variety of molecular loads. The structure of the motor was first derivatized by means of two sequential cross-coupling reactions involving a penta(4-halogenophenyl)cyclopentadienyl hydrotris(indazolyl)borate ruthenium(II) precursor and the resulting benzylamine derivative was next exploited as key intermediate in the divergent synthesis of a family of nanowinch prototypes. A one-pot method involving sequential peptide coupling and Cu-catalyzed azide-alkyne cycloaddition was developed to yield four loaded nanowinches, with load fragments encompassing triptycene, fullerene and porphyrin moieties.