72453-37-3

Basic information

• Product Name: (1R,5R)-6,6-Dimethyl-3-(E)-ethylidenebicyclo<3.1.1>heptan-2-one
• Synonyms: (1R,5R)-6,6-Dimethyl-3-(E)-ethylidenebicyclo<3.1.1>heptan-2-one
• CAS NO: 72453-37-3
• Molecular Weight: 164.247
• Mol File: 72453-37-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (1R,5R)-6,6-Dimethyl-3-(E)-ethylidenebicyclo<3.1.1>heptan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,5R)-6,6-Dimethyl-3-(E)-ethylidenebicyclo<3.1.1>heptan-2-one(72453-37-3)
• EPA Substance Registry System: (1R,5R)-6,6-Dimethyl-3-(E)-ethylidenebicyclo<3.1.1>heptan-2-one(72453-37-3)

Safety Data

• Hazardous Substances Data: 72453-37-3(Hazardous Substances Data)

Upstream product

• 38651-65-9 (1R,5S)-(+)-nopinone 
• 75-07-0 acetaldehyde 

Downstream Products

• 15764-04-2 (4R,4aS)-(+)-4,4a-dimethyl-6-isopropylidene-4,4a,5,6,7,8-hexahydro-(3H)-naphthalen-2-one 
• 4674-50-4 (+)-nootkatone 

Relevant articles and documents

An efficient and economic asymmetric synthesis of (+)-nootkatone, tetrahydronootkatone, and derivatives

Image Persented A facile route to enantiomerically pure (+)-nootkatone and derivatives has been established through conjunctive stereoselective Grignard/anionic oxy-Cope (AOC) reactions.

Efficient and economic asymmetric synthesis of nootkatone, tetrahydronootkatone, their precursors and derivatives

An inexpensive, stereoselective synthesis for nootkatone, tetrahydronootkatone, and their derivatives is disclosed. The starting materials used in the synthesis are inexpensive. The principal starting material, (?)-β-Pinene, is on the GRAS list (generally recognized as safe).