724733-47-5

Basic information

• Product Name: 6-(4-bromobenzyloxy)-3-deoxy-1,2-O-isopropylidene-D-glucose
• Synonyms: 6-(4-bromobenzyloxy)-3-deoxy-1,2-O-isopropylidene-D-glucose
• CAS NO: 724733-47-5
• Molecular Weight: 373.244
• Mol File: 724733-47-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-(4-bromobenzyloxy)-3-deoxy-1,2-O-isopropylidene-D-glucose(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(4-bromobenzyloxy)-3-deoxy-1,2-O-isopropylidene-D-glucose(724733-47-5)
• EPA Substance Registry System: 6-(4-bromobenzyloxy)-3-deoxy-1,2-O-isopropylidene-D-glucose(724733-47-5)

Safety Data

• Hazardous Substances Data: 724733-47-5(Hazardous Substances Data)

Upstream product

• 4005-46-3 3-deoxy-1,2-O-isopropylidene-D-glucose 
• 589-15-1 1-bromomethyl-4-bromobenzene 

Downstream Products

• 724733-56-6 Pyridine-2-carboxylic acid ((S)-1-{(1S,2S)-1-(4-bromo-benzyloxymethyl)-3-[(S)-1-((S)-1-carbamoyl-3-methyl-butylcarbamoyl)-ethylcarbamoyl]-2-hydroxy-propylcarbamoyl}-2-methyl-propyl)-amide 
• 724733-67-9 N-{(1S,2S)-1-(4-Bromo-benzyloxymethyl)-3-[(S)-1-((S)-1-carbamoyl-3-methyl-butylcarbamoyl)-ethylcarbamoyl]-2-hydroxy-propyl}-2,4,6-trifluoro-benzamide 
• 724733-73-7 N-{(1S,2S)-1-(4-Bromo-benzyloxymethyl)-2-hydroxy-3-[2-(3-methoxy-phenyl)-ethylcarbamoyl]-propyl}-2,4,6-trifluoro-benzamide 
• 724733-74-8 N-[(1S,2S)-1-(4-Bromo-benzyloxymethyl)-3-cyclohexylcarbamoyl-2-hydroxy-propyl]-2,4,6-trifluoro-benzamide 
• 724733-64-6 Pyridine-2-carboxylic acid {(S)-1-[(1S,2S)-1-(4-bromo-benzyloxymethyl)-3-butylcarbamoyl-2-hydroxy-propylcarbamoyl]-2-methyl-propyl}-amide 
• 724733-51-1 (3S,4S)-4-azido-5-(4-bromobenzyloxy)-3-hydroxypentanoic acid methyl ester 
• 724733-49-7 5-azido-3,5-dideoxy-6-O-(4-bromobenzyl)-1,2-O-isopropylidene-L-lyxo-hexofuranose 

Relevant articles and documents

Design and synthesis of potent inhibitors of the malaria aspartyl proteases plasmepsin I and II. Use of solid-phase synthesis to explore novel statine motifs

Picomolar to low nanomolar inhibitors of the two aspartic proteases plasmepsin (Plm) I and II, from the malaria parasite Plasmodium falciparum, have been identified from sets of libraries containing novel statine-like templates modified at the amino and c

AMIDE DERIVATIVES AS INHIBITORS OF ASPARTYL PROTEASES

The invention provides compounds of the formula (I). N-oxides, addition salts, quaternary amines, metal complexes, stereochemically isomeric forms and metabolites thereof, wherein W is H,C 1-C 6 alkyl, C 3-C 6 cycloalkyl, aryl or heterocyclyl; Q is aryl or heterocyclyl; A is a five or six membered saturated, partially unsaturated or aromatic ring; D is (II) or (III) the other variables are as defined in the specification. The compounds of the invention are inhibitors of BACE and are among other things useful for the treatment and/or prevention of conditions associated with BACE activity such as Alzheimer's disease.