7249-51-6 Usage
Description
N-[2-(dimethylamino)ethyl]formamide, also known as N,N-dimethyl-2-formamidoethylamine, is a chemical compound that features a formamide group connected to a dimethylaminoethyl side chain. It is recognized for its versatility in organic synthesis and pharmaceutical manufacturing, serving as a valuable building block. N-[2-(dimethylamino)ethyl]formamide is adept at participating in a range of chemical reactions such as acylation, alkylation, and amidation. Moreover, it exhibits utility as a solvent in chemical processes and as a stabilizer in pharmaceutical formulations, and it can act as a chelating agent for metal ions in solution.
Uses
Used in Pharmaceutical Industry:
N-[2-(dimethylamino)ethyl]formamide is utilized as a building block in the synthesis of various pharmaceutical compounds, contributing to the development of new drugs and medicines. Its ability to engage in multiple types of chemical reactions facilitates the creation of a wide array of molecular structures, which is essential for drug discovery and innovation.
Used in Agrochemical Industry:
In the agrochemical sector, N-[2-(dimethylamino)ethyl]formamide serves as a key component in the synthesis of pesticides and other agricultural chemicals. Its reactivity and functional group compatibility make it suitable for the production of effective and targeted agrochemicals.
Used in Materials Science:
N-[2-(dimethylamino)ethyl]formamide is also applied within the field of materials science, where it can be used to develop new materials with specific properties. Its role as a building block allows for the engineering of materials with tailored characteristics for various applications.
Used as a Solvent in Chemical Reactions:
N-[2-(dimethylamino)ethyl]formamide functions as a solvent in various chemical processes, providing a medium for reactions to occur. Its properties may offer advantages such as increased reaction rates or selectivity, making it a preferred choice in certain chemical procedures.
Used as a Stabilizer in Pharmaceutical Formulations:
N-[2-(dimethylamino)ethyl]formamide contributes to the stability of pharmaceutical formulations, ensuring the longevity and efficacy of drugs. Its stabilizing properties can be crucial for maintaining the quality and performance of medications over time.
Used as a Chelating Agent for Metal Ions:
In solution, this compound can act as a chelating agent, binding to metal ions. This capability is beneficial in various applications, such as in the purification of metal ions or in the development of metal-based catalysts.
Check Digit Verification of cas no
The CAS Registry Mumber 7249-51-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,4 and 9 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 7249-51:
(6*7)+(5*2)+(4*4)+(3*9)+(2*5)+(1*1)=106
106 % 10 = 6
So 7249-51-6 is a valid CAS Registry Number.
7249-51-6Relevant articles and documents
Amide-ligand-controlled highly para-selective arylation of monosubstituted simple arenes with arylboronic acids
Luan, Yu-Xin,Zhang, Tao,Yao, Wei-Wei,Lu, Ke,Kong, Lu-Yao,Lin, Yu-Tong,Ye, Mengchun
supporting information, p. 1786 - 1789 (2017/02/15)
Pd-catalyzed highly para-selective arylations of monosubstituted simple arenes with arylboronic acids to widely existed biaryls have been developed. Inspired by requisite amide-directing groups in reported selective oxidative couplings, amide ligands, especially DMF, are designed and found to be critical for the selectivity control in current arylations.
Long-range anisotropic effects of long chain amides
Budzikiewicz, Herbert,Vieth, Peter-Eric,Krueger, Uwe
, p. 825 - 840 (2007/10/02)
In 1H-NMR spectra of amids with long-chain aliphatic N-substituents one observes - despite of the free mobility of the aliphatic chain - splitting of the signals of the terminal methyl groups which is caused by the hindered rotation of the amide bond. - Keywords: Amides; Hindered rotation; 1H-NMR
