725-75-7Relevant articles and documents
On the purity of 2-[ortho-anilinyl]-1,3-benzoxazole derived from 2H-3,1-benzoxazine-2,4(1H)dione (isatoic anhydride) [1,2]
Button, Karen M.,Gossage, Robert A.,Jenkins, Hilary A.,Mahdi, Tayseer,Resanovic, Sanja
, p. 268 - 271 (2010)
(Chemical Equation Presented) The Lewis acid catalyzed synthesis and chromatographic purification of isatoic anhydride-derived 2-(2′-anilinyl)- 1,3-benzoxazole (2) can result in the co-isolation of 2 and a light pink colored impurity (a predictable intermediate in the formation of 2. Compound 3 crystallizes in an orthorhombic crystal system of space group P2 12121 with four molecules in the unit cell (α = β = γ = 90°; a = 6.715 (2) A, b = 12.100 (4) A, c = 13.321 (4) A; V = 1082.2 (6) A3). Pure 2 is characterized as a colorless, high-melting solid; unlike the dark colored oil that is isolated if 2 contains traces of 3.
Quinazolinone derivatives and production method and application thereof
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Paragraph 0082, (2020/02/14)
The invention discloses quinazolinone derivatives and a production method and application thereof. The quinazolinone derivatives are synthesized by means of the simple and convenient method, the yields are high, the production cost is low, with a concentr